The rat MIS1/Pvt-1 locus is syntenic with MYC on chromosome 7.
作者信息
Ingvarsson S, Wirschubsky Z, Szpirer J, Levan G, Klein G, Sümegi J
机构信息
Department of Tumor Biology, Karolinska Institutet, Stockholm, Sweden.
出版信息
Cytogenet Cell Genet. 1987;45(3-4):174-6. doi: 10.1159/000132450.
PMID:3691183
Abstract
Mouse Pvt-1 and rat MIS1 are frequent proviral integration sites in retrovirally induced lymphomas. The Pvt-1 locus is also involved in mouse plasmacytoma (6;15) and in the variant Burkitt lymphoma (2;8) translocations. We show that the Pvt-1/MIS1 locus is syntenic with MYC on rat chromosome 7. This is consistent with a postulate of close linkage and, possibly, a functional relationship between the MYC protooncogene and the MIS1/Pvt-1 locus.
摘要
Zotero 插件