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卡介苗膀胱内灌注治疗膀胱癌后并发赖特综合征:病例报告

Reiter's syndrome following intravesical Bacillus Calmette-Guerin therapy for bladder carcinoma: Case report.

作者信息

Alsulami Hajar Aown Allah, Al-Nashiwaty Omar, Khalifa Mahassen Aly, Syed Nazar Ulla, Ahmed Noha, Almuthree Souad

机构信息

King Abdullah Medical city, Makkah, Saudi Arabia.

Blackpool Victoria Hospital, London, UK.

出版信息

IDCases. 2023 Feb 19;31:e01711. doi: 10.1016/j.idcr.2023.e01711. eCollection 2023.

Abstract

Reiter syndrome is an autoimmune condition that develops in as a reactive response to GI or GU related infectious and rarely related to Intravesical BCG. it is a triad of conjunctivitis, urethritis, and arthritis. Here we report the case of a female patient who developed acute Reiter's syndrome following intravesical Bacillus Calmette-Guerin (BCG) immunotherapy for superficial bladder cancer. After the sixth dose in the maintenance phase of treatment the patient developed conjunctivitis, aseptic urethritis, and polyarthritis consistent with a diagnosis of Reiter's syndrome. In this patient non-steroidal anti-inflammatory drugs (NSAIDs), oral steroids and anti-tuberculosis drugs were administered with complete resolution of symptoms.

摘要

赖特综合征是一种自身免疫性疾病,作为对胃肠道或泌尿生殖道相关感染的反应而发生,很少与膀胱内卡介苗相关。它是结膜炎、尿道炎和关节炎的三联征。在此,我们报告一例女性患者,该患者在接受浅表性膀胱癌膀胱内卡介苗免疫治疗后发生急性赖特综合征。在治疗维持阶段的第六剂后,患者出现结膜炎、无菌性尿道炎和多关节炎,并符合赖特综合征的诊断。该患者接受了非甾体抗炎药、口服类固醇和抗结核药物治疗,症状完全缓解。

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