Pye Katherine, Jackson Hannah, Iacono Teresa, Shiell Alan
School of Health and Social Development, Deakin University, Geelong, Australia.
Monash Centre for Health Research and Implementation, Monash University, Melbourne, Australia.
J Autism Dev Disord. 2024 May;54(5):1691-1711. doi: 10.1007/s10803-023-05938-3. Epub 2023 Mar 13.
Many autistic children access some form of early intervention, but little is known about the value for money of different programs. We completed a scoping review of full economic evaluations of early interventions for autistic children and/or their families. We identified nine studies and reviewed their methods and quality. Most studies involved behavioral interventions. Two were trial-based, and the others used various modelling methods. Clinical measures were often used to infer dependency levels and quality-adjusted life-years. No family-based or negative outcomes were included. Authors acknowledged uncertain treatment effects. We conclude that economic evaluations in this field are sparse, methods vary, and quality is sometimes poor. Economic research is needed alongside longer-term clinical trials, and outcome measurement in this population requires further exploration.
许多自闭症儿童都接受了某种形式的早期干预,但对于不同项目的性价比却知之甚少。我们对自闭症儿童及其家庭早期干预的全面经济评估进行了一项范围审查。我们识别出9项研究,并对其方法和质量进行了审查。大多数研究涉及行为干预。两项基于试验,其他则使用了各种建模方法。临床指标常被用于推断依赖程度和质量调整生命年。未纳入基于家庭的或负面结果。作者承认治疗效果存在不确定性。我们得出结论,该领域的经济评估较少,方法各异,质量有时较差。除了长期临床试验,还需要进行经济研究,并且该人群的结果测量需要进一步探索。