• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

胰腺受累于厄尔德海姆-切斯特病：一种罕见疾病的罕见表现。

Pancreatic involvement in Erdheim-Chester disease: Rare presentation of a rare disease.

作者信息

Rafiee Moezedin Javad, Taylor Jana, Hickeson Marc, Friedrich Matthias G, Chetrit Michael

机构信息

Department of Medicine and Diagnostic Radiology, McGill University Health Centre, 1001 Blvd, Decarie, Montreal, Québec, H4A3J1 Canada.

Department of Diagnostic Radiology, McGill University Health Centre, 1001 Blvd, Decarie, Montreal, Québec, H4A3J1, Canada.

出版信息

Radiol Case Rep. 2023 Mar 4;18(5):1809-1820. doi: 10.1016/j.radcr.2023.02.012. eCollection 2023 May.

DOI:10.1016/j.radcr.2023.02.012
PMID:36915608
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10006724/
Abstract

Erdheim-Chester disease (ECD) as a rare non-Langerhans histiocytosis has various clinical manifestations. It is characterized histologically by infiltration of every organ, more commonly bone, retroperitoneum, cardiovascular and CNS systems with foamy, lipid -laden macrophage. Pancreatic involvement as a manifestation of this uncommon disease has very rarely been reported. Here we report a 73-year-old woman with ECD and pancreas involvement in CT, MRI and PET scans. We also aim to increase radiologist knowledge about considering ECD as a differential diagnosis for pancreas mass in the appropriate clinical situation.

摘要

Erdheim-Chester病（ECD）作为一种罕见的非朗格汉斯组织细胞增多症，有多种临床表现。其组织学特征为每个器官均有浸润，更常见于骨骼、腹膜后、心血管和中枢神经系统，伴有泡沫状、富含脂质的巨噬细胞。作为这种罕见疾病的一种表现，胰腺受累的报道极为罕见。在此，我们报告一名73岁女性，其在CT、MRI和PET扫描中显示患有ECD且胰腺受累。我们还旨在提高放射科医生在适当临床情况下将ECD视为胰腺肿块鉴别诊断的认识。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2aee/10006724/d7567ee68d33/gr13.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2aee/10006724/109df00217e3/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2aee/10006724/9ca8472fccb4/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2aee/10006724/d37bbdca987f/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2aee/10006724/1121b99063b2/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2aee/10006724/1bfacb54fb8b/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2aee/10006724/215cbc33a265/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2aee/10006724/5572aabdcc50/gr7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2aee/10006724/b28f4f2fce25/gr8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2aee/10006724/8cf79652be09/gr9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2aee/10006724/690d540b7b8b/gr10.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2aee/10006724/e3367b365d7d/gr11.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2aee/10006724/ae035c5a5985/gr12.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2aee/10006724/d7567ee68d33/gr13.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2aee/10006724/109df00217e3/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2aee/10006724/9ca8472fccb4/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2aee/10006724/d37bbdca987f/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2aee/10006724/1121b99063b2/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2aee/10006724/1bfacb54fb8b/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2aee/10006724/215cbc33a265/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2aee/10006724/5572aabdcc50/gr7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2aee/10006724/b28f4f2fce25/gr8.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2aee/10006724/8cf79652be09/gr9.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2aee/10006724/690d540b7b8b/gr10.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2aee/10006724/e3367b365d7d/gr11.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2aee/10006724/ae035c5a5985/gr12.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2aee/10006724/d7567ee68d33/gr13.jpg

相似文献

1
Pancreatic involvement in Erdheim-Chester disease: Rare presentation of a rare disease.胰腺受累于厄尔德海姆-切斯特病：一种罕见疾病的罕见表现。
Radiol Case Rep. 2023 Mar 4;18(5):1809-1820. doi: 10.1016/j.radcr.2023.02.012. eCollection 2023 May.
2
Pancreatic involvement in Erdheim-Chester disease: a case report and review of the literature.胰腺埃勒-狄克森病（ Erdheim-Chester disease ）：病例报告及文献复习。
BMC Gastroenterol. 2022 Jun 21;22(1):302. doi: 10.1186/s12876-022-02378-8.
3
(18)F-FDG positron emission tomography/computed tomography and (99m)Tc-MDP skeletal scintigraphy in a case of Erdheim-Chester disease.18F-氟代脱氧葡萄糖正电子发射断层扫描/计算机断层扫描及99m锝-亚甲基二膦酸盐骨闪烁显像在1例厄尔海姆-切斯特病中的应用
Hell J Nucl Med. 2011 Sep-Dec;14(3):311-2.
4
Erdheim-Chester disease involving the breast--a rare but important differential diagnosis.累及乳腺的 Erdheim-Chester 病——一种罕见但重要的鉴别诊断。
Hum Pathol. 2015 Jan;46(1):159-64. doi: 10.1016/j.humpath.2014.10.005. Epub 2014 Oct 18.
5
[Diagnosis and Treatment of Erdheim-Chester Disease -Review].[ Erdheim-Chester病的诊断与治疗——综述]
Zhongguo Shi Yan Xue Ye Xue Za Zhi. 2016 Aug;24(4):1256-9. doi: 10.7534/j.issn.1009-2137.2016.04.055.
6
Erdheim-Chester disease with multisystem involvement evaluated by multimodal imaging: A case report.多模态影像学评估的累及多系统的 Erdheim-Chester 病：一例报告
Radiol Case Rep. 2021 Dec 30;17(3):784-789. doi: 10.1016/j.radcr.2021.11.076. eCollection 2022 Mar.
7
Diagnosis of Erdheim-Chester disease by using computerized tomography-guided stereotactic biopsy of a caudate lesion. Case report.通过计算机断层扫描引导下对尾状核病变进行立体定向活检诊断厄德里希-切斯特病。病例报告。
J Neurosurg. 2004 Sep;101(3):521-7. doi: 10.3171/jns.2004.101.3.0521.
8
Thoracic, abdominal and musculoskeletal involvement in Erdheim-Chester disease: CT, MR and PET imaging findings. Erdheim-Chester 病的胸部、腹部和肌肉骨骼累及：CT、MR 和 PET 成像表现。
Insights Imaging. 2014 Aug;5(4):473-82. doi: 10.1007/s13244-014-0331-7. Epub 2014 Jul 14.
9
Cardiovascular Involvement in Erdheim-Chester Disease: A Case Report and Review of the Literature.Erdheim-Chester病的心血管受累：一例报告及文献复习
Medicine (Baltimore). 2015 Oct;94(43):e1365. doi: 10.1097/MD.0000000000001365.
10
Unusual manifestation of Erdheim-Chester disease.罕见的 Erdheim-Chester 病表现。
BMC Gastroenterol. 2011 Jun 22;11:77. doi: 10.1186/1471-230X-11-77.

引用本文的文献

1
Case Report: The rare pancreatic involvement in Erdheim-Chester disease.病例报告：厄尔德海姆-切斯特病罕见的胰腺受累情况。
Front Immunol. 2025 Jul 14;16:1611452. doi: 10.3389/fimmu.2025.1611452. eCollection 2025.
2
Erdheim-Chester Disease with Pancreatic Enlargement Observed Using Contrast-enhanced Endoscopic Ultrasonography.使用对比增强内镜超声观察到的伴有胰腺肿大的 Erdheim-Chester 病。
Intern Med. 2025 Jan 15;64(2):231-236. doi: 10.2169/internalmedicine.3864-24. Epub 2024 May 30.
3
Double Subclavian Steal Syndrome As Initial Manifestation of Erdheim-Chester Disease: A Case Report.

本文引用的文献

1
Prevalence, patterns and outcomes of cardiac involvement in Erdheim-Chester disease.Erdheim-Chester病心脏受累的患病率、模式及转归
Eur Heart J. 2023 Jul 7;44(26):2376-2385. doi: 10.1093/eurheartj/ehac741.
2
Pancreatic involvement in Erdheim-Chester disease: a case report and review of the literature.胰腺埃勒-狄克森病（ Erdheim-Chester disease ）：病例报告及文献复习。
BMC Gastroenterol. 2022 Jun 21;22(1):302. doi: 10.1186/s12876-022-02378-8.
3
Erdheim-Chester Disease: a Rare but Important Cause of Recurrent Pericarditis.
双锁骨下动脉盗血综合征作为 Erdheim-Chester 病的初始表现：一例报告
Cureus. 2023 Dec 13;15(12):e50427. doi: 10.7759/cureus.50427. eCollection 2023 Dec.
厄德海姆-切斯特病：复发性心包炎的一种罕见但重要病因。
Curr Cardiol Rep. 2020 Jun 30;22(8):75. doi: 10.1007/s11886-020-01307-z.
4
Erdheim-Chester disease: a rapidly evolving disease model.厄德海姆-切斯特病：一种快速演变的疾病模型。
Leukemia. 2020 Nov;34(11):2840-2857. doi: 10.1038/s41375-020-0944-4. Epub 2020 Jun 26.
5
Erdheim-Chester disease: consensus recommendations for evaluation, diagnosis, and treatment in the molecular era.骨硬化性嗜酸性肉芽肿：分子时代下的评估、诊断和治疗的共识建议。
Blood. 2020 May 28;135(22):1929-1945. doi: 10.1182/blood.2019003507.
6
Erdheim-Chester disease.额颞叶痴呆。
Blood. 2020 Apr 16;135(16):1311-1318. doi: 10.1182/blood.2019002766.
7
Cardiothoracic manifestations of Erdheim-Chester disease. Erdheim-Chester 病的心胸表现。
Br J Radiol. 2019 Dec;92(1104):20190473. doi: 10.1259/bjr.20190473. Epub 2019 Aug 14.
8
Efficacy of MEK inhibition in patients with histiocytic neoplasms.MEK 抑制在组织细胞肿瘤患者中的疗效。
Nature. 2019 Mar;567(7749):521-524. doi: 10.1038/s41586-019-1012-y. Epub 2019 Mar 13.
9
Cardiovascular manifestations of Erdheim-Chester disease.Erdheim-Chester病的心血管表现
Echocardiography. 2019 Feb;36(2):229-236. doi: 10.1111/echo.14231. Epub 2018 Dec 20.
10
Thoracic involvement in Erdheim-Chester disease: computed tomography imaging findings and their association with the BRAF mutation. Erdheim-Chester 病的胸部受累：计算机断层扫描成像表现及其与 BRAF 突变的关系。
Eur Radiol. 2018 Nov;28(11):4635-4642. doi: 10.1007/s00330-018-5421-3. Epub 2018 May 7.