Kavanagh Francene, Singhal Shaani, Rozen Warren M
Department of Plastic and Reconstructive Surgery, Peninsula Clinical School, Central Clinical School, Faculty of Medicine, Monash University, Frankston, Australia.
Gland Surg. 2023 Feb 28;12(2):297-301. doi: 10.21037/gs-22-468. Epub 2023 Feb 3.
Split thickness skin graft (STSG) is a routine reconstructive manoeuvre, particularly after excision of cutaneous lower limb malignancies. While surgical technique is well established, evidence supporting the postoperative management of these grafts is less robust. Compression therapy after the index procedure may be an important adjunct for graft take and minimizing complications, particularly in patients susceptible to oedema from a concurrent lymph node procedure.
An initial PubMed literature search was performed using the terms "split thickness skin graft", "compression" and "oedema" yielding no results, hence a broader search was performed combining the terms "compression", "pressure" and "split thickness skin graft" providing 383 results. One hundred articles remained for abstract review after an initial screen.
The literature on compression therapy to promote split thickness graft take is modest, with only 12 articles described (12/100, 12.0%). Even then, none of these were in the setting of grafting after oncological resection. Many of the articles promote negative pressure wound therapy (NPWT) as an established adjunct to promote graft take (80/100, 80.0%).
There is limited demonstrated efficacy of postoperative compression therapy for lower limb STSG let alone in patients with an ancillary lymph node procedure. Further large-scale trials ideally in a prospective fashion are warranted to validate this as a simple, widely available and cost-effective adjunct to STSG in this particularly susceptible population of reconstructive patients.
断层皮片移植(STSG)是一种常规的重建手术,尤其是在切除下肢皮肤恶性肿瘤之后。虽然手术技术已很成熟,但支持这些移植术后管理的证据并不充分。初次手术后的加压治疗可能是促进移植皮片成活并减少并发症的重要辅助手段,特别是对于因同时进行淋巴结手术而易于发生水肿的患者。
最初在PubMed数据库中使用“断层皮片移植”“加压”和“水肿”等关键词进行文献检索,未得到结果,因此进行了更广泛的检索,将“加压”“压力”和“断层皮片移植”等关键词组合起来,得到383条结果。初步筛选后,剩余100篇文章进行摘要审查。
关于加压治疗以促进断层皮片成活的文献较少,仅描述了12篇文章(12/100,12.0%)。即便如此,这些文章中没有一篇是关于肿瘤切除术后移植的情况。许多文章推荐负压伤口治疗(NPWT)作为促进皮片成活的既定辅助手段(80/100,80.0%)。
术后加压治疗对下肢断层皮片移植的疗效有限,更不用说对于同时进行淋巴结手术的患者了。理想情况下,需要进一步进行大规模前瞻性试验,以验证其作为一种简单、广泛可用且经济有效的辅助手段,应用于这类特别易受影响的重建患者群体的断层皮片移植手术。