Department of Chemical and Biological Engineering, Iowa State University, 618 Bissell Road, Ames, Iowa 50011, United States.
ACS Sens. 2023 Mar 24;8(3):943-955. doi: 10.1021/acssensors.2c02552. Epub 2023 Mar 13.
Inexpensive and accurate tools for monitoring conditions in enclosed environments (through garments, bandages, tissue, etc.) have been a long-standing goal of medicine. Passive resonant sensors are a promising solution for such wearable health sensors as well as off-body diagnostics. They are simple circuits with inherent inductance and capacitance (LC tank) that have a measurable resonant frequency. Changes in local parameters, e.g., permittivity or geometry, effect inductance and capacitance which cause a resonant frequency shift response. This signal transduction has been applied to several biomedical applications such as intracranial pressure, hemodynamics, epidermal hydration, etc. Despite these many promising applications presented in the literature, resonant sensors still do not see widespread adoption in biomedical applications, especially as wearable or embedded sensing devices. This perspective highlights some of the current challenges facing LC resonant sensors in biomedical applications, such as positional sensitivity, and potential strategies that have been developed to overcome them. An outlook on adoption in medicine and health monitoring is presented, and a perspective is given on next steps for research in this field.
长期以来，医疗领域一直致力于研发经济实惠且精确的监测封闭环境条件（通过衣物、绷带、组织等）的工具。无源谐振传感器是一种很有前途的解决方案，可用于可穿戴健康传感器以及体外诊断。它们是具有固有电感和电容（LC 槽）的简单电路，具有可测量的谐振频率。局部参数（例如介电常数或几何形状）的变化会影响电感和电容，从而导致谐振频率发生偏移响应。这种信号转换已应用于多种生物医学应用，如颅内压、血液动力学、表皮水合作用等。尽管文献中提出了许多有前途的应用，但谐振传感器在生物医学应用中仍未得到广泛采用，特别是作为可穿戴或嵌入式感测设备。本文重点介绍了 LC 谐振传感器在生物医学应用中面临的一些当前挑战，例如位置敏感性，以及为克服这些挑战而开发的潜在策略。本文还展望了 LC 谐振传感器在医学和健康监测中的应用，并对该领域的研究下一步提出了看法。
