Aix Marseille Université, C entre national de la recherche scientifique, Institut national de la santé et de la recherche médicale, Centre d'immunologie de Marseille-Luminy , Marseille, France.
J Exp Med. 2023 Apr 3;220(4). doi: 10.1084/jem.20230250. Epub 2023 Mar 14.
Tingible body macrophages in lymph node are involved in cleaning up debris from apoptotic B cells. Gurwisz et al. (2023. J. Exp. Med.https://doi.org/10.1084/jem.20222173) and Grootveld et al. (2023. Cell.https://doi.org/10.1016/j.cell.2023.02.004) report how tingible body macrophages, originating from tissue-resident macrophages, clear apoptotic B cells in the germinal center using a "stand-hunting" strategy.
淋巴结中的有被膜滤泡树突细胞状巨噬细胞参与清除凋亡 B 细胞的碎片。Gurwisz 等人(2023 年,《实验医学杂志》,https://doi.org/10.1084/jem.20222173)和 Grootveld 等人(2023 年,《细胞》,https://doi.org/10.1016/j.cell.2023.02.004)报道了有被膜滤泡树突细胞状巨噬细胞如何利用“站桩狩猎”策略,从组织驻留巨噬细胞起源,清除生发中心的凋亡 B 细胞。