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利用历史远程监测数据来确定阻塞性睡眠呼吸暂停(OSA)患者 CPAP 治疗不依从的预测因素。

Use of historical remote monitoring data to determine predictors of CPAP non-compliance in patients with OSA.

机构信息

Department of Respiratory Medicine, Aintree University Hospital, Liverpool University Hospitals NHS Foundation Trust, Liverpool, L9 7AL, UK.

Liverpool Centre for Cardiovascular Science, University of Liverpool and Liverpool Heart & Chest Hospital, Liverpool, UK.

出版信息

Sleep Breath. 2023 Oct;27(5):1899-1908. doi: 10.1007/s11325-023-02806-3. Epub 2023 Mar 14.

Abstract

PURPOSE

Continuous positive airway pressure (CPAP) is the gold standard treatment for obstructive sleep apnoea. This study aimed to use complete usage data collected remotely from modern CPAP devices to identify compliance trends and clinical predictors of CPAP usage.

METHODS

Group usage data were analysed for a large cohort at a single tertiary sleep-centre before a detailed review of a 90-day reporting window for each patient was conducted. Individual data were collected for a smaller cohort of patients including demographics, past medical history and diagnostic sleep study results. A zero-inflated negative binomial regression model was used to determine associations between patient characteristics and usage days.

RESULTS

Of 6450 patients who were prescribed CPAP and included in the initial service analysis, 476 patients were included in the sub-group. Complete usage data revealed that 46% of patients were fully compliant with CPAP therapy. Compliance fell from 55 to 46% by day 90 and remained at this rate going forward. Significant predictors of CPAP non-compliance included being in the lowest quartile of Index of Multiple Deprivation scores (most deprived) compared with the highest quartile (least deprived) (p = .005), and less severe oxygen desaturation index (ODI) on diagnosis (p = .03).

CONCLUSIONS

Complete usage data show that compliance at day 90 appears to be a good indicator of future CPAP usage. Predictors of CPAP non-compliance may include lower socioeconomic status, and lower ODI.

摘要

目的

持续气道正压通气(CPAP)是治疗阻塞性睡眠呼吸暂停的金标准。本研究旨在利用从现代 CPAP 设备远程收集的完整使用数据,确定 CPAP 使用的依从性趋势和临床预测因素。

方法

在对每位患者进行 90 天报告窗口的详细审查之前,对一个大型单中心睡眠中心的组使用数据进行了分析。对包括人口统计学、既往病史和诊断性睡眠研究结果在内的较小患者队列收集了个体数据。使用零膨胀负二项回归模型来确定患者特征与使用天数之间的关联。

结果

在被处方 CPAP 并包含在初始服务分析中的 6450 名患者中,有 476 名患者被纳入亚组。完整的使用数据显示,46%的患者完全符合 CPAP 治疗的要求。依从性从第 90 天的 55%下降到 46%,并一直保持在这个水平。CPAP 不依从的显著预测因素包括与最高四分位数(最贫困)相比处于最低四分位数的多重剥夺指数(最贫困)(p=0.005)和诊断时较低的氧减指数(ODI)(p=0.03)。

结论

完整的使用数据表明,90 天的依从性似乎是未来 CPAP 使用的良好指标。CPAP 不依从的预测因素可能包括较低的社会经济地位和较低的 ODI。

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