Quintessence Int. 2023 Jul 17;54(7):528-534. doi: 10.3290/j.qi.b3957661.
The present study aimed to evaluate the local effect of antimicrobial photodynamic therapy (aPDT) as adjunctive treatment for Grade C periodontitis in molars teeth.
Thirty-eight molar teeth from 11 patients were included in this split-mouth randomized clinical trial. The teeth were randomly divided into two groups (n = 19 each) that were submitted to conventional scaling and root planing in addition to aPDT (test group) and to scaling and root planing in addition to aPDT simulation (control group). The following periodontal parameters were obtained prior to treatment (baseline) and at 3 months after the intervention: bleeding on probing, probing depth, gingival recession, clinical attachment level, and furcation level. A 5% significance level was adopted in the statistical analysis.
Both groups exhibited improvement in the clinical parameters (P < .001). However, the reductions in bleeding on probing and probing depth were greater in the test group (P < .001). There were no significant differences in the other clinical parameters between groups (P ≥ .130).
Molar teeth treated with aPDT and scaling and root planing showed superior clinical improvement compared to those submitted only to scaling and root planing. aPDT may be used as adjunctive treatment for Grade C periodontitis affecting molar teeth since it seems to improve the clinical response to conventional debridement.
本研究旨在评估抗菌光动力疗法（aPDT）作为磨牙 C 级牙周炎辅助治疗的局部效果。
这项随机分组的临床研究共纳入了 11 名患者的 38 颗磨牙。这些牙齿被随机分为两组（每组 19 颗），分别接受常规牙周刮治和根面平整术加 aPDT（实验组）以及牙周刮治和根面平整术加 aPDT 模拟治疗（对照组）。在治疗前（基线）和干预后 3 个月，分别测量以下牙周参数：探诊出血、探诊深度、牙龈退缩、临床附着水平和牙周袋附着水平。统计分析采用 5%的显著性水平。
两组的临床参数均有所改善（P<0.001）。然而，实验组的探诊出血和探诊深度减少更为显著（P<0.001）。两组之间的其他临床参数无显著差异（P≥0.130）。
与仅接受牙周刮治和根面平整术的磨牙相比，接受 aPDT 和牙周刮治和根面平整术治疗的磨牙具有更好的临床改善效果。aPDT 可作为磨牙 C 级牙周炎的辅助治疗方法，因为它似乎可以改善常规清创术的临床反应。
