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脊柱手术中的骨骼健康优化(BHO)

Bone Health Optimization (BHO) in Spine Surgery.

作者信息

Anderson Paul A, Binkley Neil C, Bernatz James T

机构信息

Department of Orthopedics & Rehabilitation, University of Wisconsin School of Medicine and Public Health.

Divisions of Endocrinology and Geriatrics, Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, WI.

出版信息

Spine (Phila Pa 1976). 2023 Jun 1;48(11):782-790. doi: 10.1097/BRS.0000000000004618. Epub 2023 Mar 13.

Abstract

STUDY DESIGN

Literature review.

OBJECTIVE

To educate spine surgeons on the importance of bone health optimization in surgical patients.

SUMMARY OF BACKGROUND DATA

Osteoporosis is common and underdiagnosed in spine surgery patients. Poor bone health has been linked to worse outcomes and complications after spine surgery. Guidelines are available to inform decision making on screening and treatment in this population.

METHODS

Available literature is reviewed regarding bone health screening and treatment. Studies reporting outcomes related to osteoporosis, bone density, and vitamin D status are summarized. Pharmacologic treatment and nutritional considerations are discussed. Bone health optimization practice models and outcomes are also reviewed.

RESULTS

Bone health screening should be considered in all adults over age 50. Gender-specific guidelines are available to determine which patients need dual-energy x-ray absorptiometry. Osteoporosis can be diagnosed by dual-energy x-ray absorptiometry T-score, fracture risk calculator or by history of low-energy fracture. Advanced imaging including computed tomography and magnetic resonance imaging can be used to opportunistically assess bone health. If diagnosed, osteoporosis can be treated with either antiresorptive or anabolic agents. These medications can be started preoperatively or postoperatively and, in high-risk patients, surgical delay can be considered. The implementation of bone health optimization programs has been shown to greatly increasing screening and treatment rates.

CONCLUSION

Bone health assessment and optimization are important for decreasing surgical risks and improving outcomes in spine surgery patients.

摘要

研究设计

文献综述。

目的

让脊柱外科医生了解优化手术患者骨骼健康的重要性。

背景数据总结

骨质疏松症在脊柱手术患者中很常见且诊断不足。骨骼健康状况不佳与脊柱手术后更差的预后和并发症有关。有指南可用于指导该人群筛查和治疗的决策。

方法

对有关骨骼健康筛查和治疗的现有文献进行综述。总结报告与骨质疏松症、骨密度和维生素D状态相关结果的研究。讨论药物治疗和营养方面的考虑因素。还回顾了骨骼健康优化实践模式和结果。

结果

所有50岁以上的成年人都应考虑进行骨骼健康筛查。有针对特定性别的指南来确定哪些患者需要进行双能X线吸收测定。骨质疏松症可通过双能X线吸收测定T值、骨折风险计算器或低能量骨折病史来诊断。包括计算机断层扫描和磁共振成像在内的先进成像技术可用于机会性评估骨骼健康。如果确诊,骨质疏松症可用抗吸收或促合成药物治疗。这些药物可在术前或术后开始使用,对于高危患者,可考虑推迟手术。骨骼健康优化计划的实施已被证明能大大提高筛查和治疗率。

结论

骨骼健康评估和优化对于降低脊柱手术患者的手术风险和改善预后很重要。

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