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数字化抗菌药物管理决策支持以改善抗菌药物管理。

Digital Antimicrobial Stewardship Decision Support to Improve Antimicrobial Management.

机构信息

Department of Pediatrics, Division of General Pediatrics, Boston Children's Hospital, Boston, Massachusetts, United States.

Novant Health Eastover Pediatrics, Charlotte, North Carolina, United States.

出版信息

Appl Clin Inform. 2023 May;14(3):418-427. doi: 10.1055/a-2054-0270. Epub 2023 Mar 14.

Abstract

OBJECTIVES

We sought to create a digital application to support clinicians in empiric and pathogen-directed antibiotic ordering based on local susceptibility patterns and evidence-based treatment durations, thereby promoting antimicrobial stewardship.

METHODS

We formed a multidisciplinary team that met bimonthly from 2017 to 2018 to design and construct a web-based antimicrobial stewardship platform called Antibiogram + . We used an iterative and agile technical development process with frequent feedback from clinicians.

RESULTS

Antibiogram+ is an online tool, accessible via the electronic health record and hospital intranet, which offers institutional antibiotic susceptibilities for major pathogens, recommendations for empiric antibiotic selection and treatment durations for common pediatric conditions, antimicrobial dosing and monitoring guidance, and links to other internal clinical decision support resources. The tool was accessed 11,823 times with 492 average monthly views during the first 2 years after release. Compared with use of a preexisting print antibiogram and dosing card, pediatric residents more frequently reported "often" being sure of antibiotic dosing with Antibiogram+ (58 vs. 15%,  < 0.01). Respondents also reported improved confidence in choice of antibiotic, but this finding did not reach statistical significance (55 vs. 35%,  = 0.26).

CONCLUSION

We report the successful development of a digital antimicrobial stewardship platform with consistent rates of access during the first 2 years following release and improved provider comfort with antibiotic management.

摘要

目的

我们旨在创建一个数字应用程序,基于当地药敏模式和循证治疗持续时间,为临床医生提供经验性和靶向性抗生素用药的支持,从而促进抗菌药物管理。

方法

我们成立了一个多学科团队,从 2017 年到 2018 年,每两个月开会一次,设计并构建了一个名为 Antibiogram+的基于网络的抗菌药物管理平台。我们采用迭代和敏捷的技术开发过程,并经常从临床医生那里获得反馈。

结果

Antibiogram+是一个在线工具,可以通过电子病历和医院内部网访问,提供主要病原体的机构抗生素药敏性、常见儿科疾病的经验性抗生素选择和治疗持续时间的建议、抗菌药物剂量和监测指南,以及与其他内部临床决策支持资源的链接。该工具在发布后的头 2 年中被访问了 11823 次,平均每月有 492 次访问。与使用现有的印刷版药敏图和剂量卡相比,儿科住院医师更频繁地报告说,使用 Antibiogram+时,他们“经常”确定抗生素剂量(58% 比 15%,<0.01)。受访者还报告说,他们对抗生素选择的信心有所提高,但这一发现没有达到统计学意义(55% 比 35%,=0.26)。

结论

我们报告了一个数字抗菌药物管理平台的成功开发,该平台在发布后的头 2 年中保持了稳定的访问率,并提高了临床医生对抗生素管理的信心。

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Antimicrobial stewardship and antibiograms: importance of moving beyond traditional antibiograms.抗菌药物管理与抗菌谱:超越传统抗菌谱的重要性
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