Sanders Gabrielle
Obstetrics and Gynaecology, Colchester Hospital, East Suffolk and North Essex NHS Foundation Trust, Colchester, UK
BMJ Case Rep. 2023 Mar 14;16(3):e252602. doi: 10.1136/bcr-2022-252602.
Peppermint oil capsules are prescribed to manage abdominal colic and distension, a common complaint in postcaesarean section patients. Arachis (peanut) oil is contained within one frequently prescribed peppermint formulation: Colpermin. This ingredient is contraindicated in patients with peanut and soya allergy; however, this is not stated in the side effects or contraindications section of the British National Formulary, or present on the medication packaging. A postpartum woman in her early 30s had an unexpected allergic reaction to the capsules, in the form of a generalised body rash, fortunately with no anaphylactic features. The patient reported the same reaction to soya in the past. After review of the patient's clinical and medication history, Colpermin capsules were thought to be responsible for the patient's symptoms. This case highlights the necessity for clearer documentation in prescribing formularies and on medication packaging to ensure patient safety.
薄荷油胶囊被用于治疗腹部绞痛和腹胀,这是剖宫产术后患者的常见症状。一种常用的薄荷制剂Colpermin中含有花生油。对花生和大豆过敏的患者禁用该成分;然而,英国国家处方集的副作用或禁忌部分未提及这一点,药品包装上也未标明。一名30岁出头的产后女性对这些胶囊出现了意外的过敏反应,表现为全身性皮疹,所幸没有过敏特征。该患者曾报告过去对大豆有相同反应。在查阅患者的临床和用药史后,认为Colpermin胶囊是导致患者症状的原因。该病例凸显了在处方集和药品包装上进行更清晰记录以确保患者安全的必要性。