苯乳酸和苯丙酮酸对硬脂酰辅酶A去饱和酶的抑制作用。
The inhibition of stearoyl-coenzyme A desaturase by phenyllactate and phenylpyruvate.
作者信息
Scott W, Foote J L
出版信息
Biochim Biophys Acta. 1979 Apr 27;573(1):197-200. doi: 10.1016/0005-2760(79)90186-3.
PMID:36919
Abstract
The inhibition of oleic acid from stearic acid was studied using a rat liver microsomal preparation. Phenyllactic acid and phenylpyruvic acid are partially inhibitory. The may be related to the low oleic acid to stearic acid ratios found in brains of phenylketonuric persons and experimentally phenylketonuric rats.
摘要
利用大鼠肝微粒体制剂研究了油酸对硬脂酸的抑制作用。苯乳酸和苯丙酮酸具有部分抑制作用。这可能与苯丙酮尿症患者及实验性苯丙酮尿症大鼠大脑中油酸与硬脂酸比例较低有关。
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