Department of Shizuoka Physical Therapy, Faculty of Health Science, Tokoha University, Shizuoka, Japan.
Department of Epidemiology for Community Health and Medicine, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Mod Rheumatol. 2024 Feb 26;34(2):414-421. doi: 10.1093/mr/road025.
Poor sleep quality, such as nocturnal arousal and sleep inefficiency, is associated with frailty and sarcopenia. Herein, we evaluated the relationship between poor sleep quality and locomotive syndrome (LS), a motor organ dysfunction common among community-dwelling middle-aged and older women.
Participants comprised 2246 Japanese middle-aged and older women. LS was classified into stages LS-1, LS-2, and LS-3 (from least to most severe) according to the results of the stand-up test, two-step test, and 25-question Geriatric Locomotive Function Scale. Sleep quality was assessed using the Pittsburgh Sleep Quality Index.
The Pittsburgh Sleep Quality Index scores were significantly higher in the LS group than that in the non-LS group (P < .001). Multivariate logistic regression analyses adjusted for potential confounders identified poor sleep quality as an independent factor of LS (odds ratio 1.59 [95% confidence interval 1.30-1.93], P < .001). Similar results were observed in the sensitivity analysis in postmenopausal women. LS and trouble sleeping because of pain showed stepwise association in all LS stages.
Poor sleep quality was independently associated with LS among community-dwelling middle-aged and older women. As the stage of LS progressed, the proportion of women with poor sleep quality increased significantly.
睡眠质量差，如夜间觉醒和睡眠效率低，与虚弱和肌肉减少症有关。在此，我们评估了睡眠质量差与行动障碍综合征（LS）之间的关系，LS 是一种常见于社区中老年女性的运动器官功能障碍。
参与者包括 2246 名日本中老年女性。根据站立测试、两步测试和 25 项老年运动功能量表的结果，LS 分为 LS-1、LS-2 和 LS-3 期（从最不严重到最严重）。使用匹兹堡睡眠质量指数评估睡眠质量。
LS 组的匹兹堡睡眠质量指数评分明显高于非 LS 组（P<.001）。调整潜在混杂因素的多变量逻辑回归分析确定睡眠质量差是 LS 的独立因素（优势比 1.59 [95%置信区间 1.30-1.93]，P<.001）。在绝经后妇女的敏感性分析中也观察到了类似的结果。在所有 LS 阶段，LS 和因疼痛而睡眠困难都表现出逐步关联。
在社区中老年女性中，睡眠质量差与 LS 独立相关。随着 LS 阶段的进展，睡眠质量差的女性比例显著增加。
