Department of Shizuoka Physical Therapy, Faculty of Health Science, Tokoha University, Shizuoka, Japan.
Department of Epidemiology for Community Health and Medicine, Kyoto Prefectural University of Medicine, Kyoto, Japan.
Mod Rheumatol. 2024 Jul 6;34(4):858-863. doi: 10.1093/mr/road096.
Evidence for an association between locomotive syndrome (LS) and depression is lacking in middle-aged women. This study aimed to investigate the relationship between LS severity and depressive symptoms in community-dwelling middle-aged women.
This cross-sectional study included 1520 middle-aged women (mean age 52 ± 6 years). LS severity was evaluated using the 25-question Geriatric Locomotive Function Scale questionnaire and motor function test. Depressive symptoms were assessed using the Zung self-rating depression scale. Multiple logistic regression analyses were performed to determine the association between depressive symptoms and LS severity, adjusting for potential confounding factors.
LS severity, as evaluated through both questionnaires and motor function tests, was significantly associated with depressive symptoms (self-rating depression scale ≥ 40 points) in middle-aged women. The relationship between LS and depressive symptoms was only significant when assessed through the 25-question Geriatric Locomotive Function Scale questionnaire rather than the motor function tests. Additionally, a stepwise association was observed between pain severity, as assessed by the 25-question Geriatric Locomotive Function Scale, and the prevalence of depressive symptoms.
LS severity is significantly associated with depressive symptoms in community-dwelling middle-aged women, suggesting the need for additional mental status assessment in participants with LS and concurrent pain.
中龄女性群体中，与行动障碍综合征（LS）和抑郁相关的证据还比较缺乏。本研究旨在调查社区居住的中龄女性 LS 严重程度与抑郁症状之间的关系。
本横断面研究纳入了 1520 名中龄女性（平均年龄 52±6 岁）。使用 25 项老年行动功能量表问卷和运动功能测试评估 LS 严重程度。使用 Zung 自评抑郁量表评估抑郁症状。采用多因素逻辑回归分析，调整潜在混杂因素后，评估抑郁症状与 LS 严重程度之间的关系。
通过问卷和运动功能测试评估的 LS 严重程度与中龄女性的抑郁症状（自评抑郁量表≥40 分）显著相关。仅当通过 25 项老年行动功能量表问卷评估时，LS 与抑郁症状之间存在显著相关性，而不是通过运动功能测试。此外，通过 25 项老年行动功能量表评估的疼痛严重程度与抑郁症状的患病率之间存在逐步关联。
LS 严重程度与社区居住的中龄女性的抑郁症状显著相关，这表明在 LS 合并疼痛的患者中需要进行额外的精神状态评估。
