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精神药物治疗前的心理健康结果:1945 年至 1954 年一个州立医院记录的回顾性病例系列。

Mental health outcomes before psychotropic medications: a retrospective case series of one state hospital records from 1945 to 1954.

机构信息

Western Michigan University, Kalamazoo, USA.

State Hospital Administration, Michigan Department of Health and Human Services, Lansing, USA.

出版信息

BMC Health Serv Res. 2023 Mar 15;23(1):257. doi: 10.1186/s12913-023-09235-8.

Abstract

BACKGROUND

Current outcomes for mental illness are widely regarded as poor. Since the introduction of psychotropic medications in the mid 1950's, previous psychosocial practices were minimized in favor of medication focused treatment. The majority of large U.S. state hospitals have closed with records destroyed or in storage, inaccessible to researchers. This creates barriers to studying and comparing outcomes before and after this shift in treatment practices.

AIMS

The study aim was to examine discharge outcomes in relation to length of stay and diagnosis in one U.S. state hospital.

METHODS

This case series study examined 5618 medical records of participants admitted to one state hospital from 1945 to 1954, the decade prior to adoption of psychotropic medications.

RESULTS

Of the 3332 individuals who left the facility, over half (59.87%) of first episode hospitalizations were discharged within 1 year, and 16.95% were hospitalized for more than 5 years. 46.17% of all admissions were discharged from hospital with no readmission. The most common diagnoses included schizophrenia, other forms of psychosis, and alcoholism. In the decade before the introduction of psychotropic medications, participants were often admitted for a single episode and returned to their homes within several years.

CONCLUSIONS

Although limited to one site, findings suggest that discharge outcomes prior to psychotropic medication as a primary treatment for mental illness may be more positive than previously understood.

摘要

背景

目前,人们普遍认为精神疾病的治疗效果不佳。自 20 世纪 50 年代中期精神药物问世以来,先前的心理社会治疗方法被最小化,转而以药物为重点的治疗方法为主。美国大多数大型州立医院已经关闭,记录被销毁或存放在存储设施中,研究人员无法获取。这为研究和比较治疗方法转变前后的结果设置了障碍。

目的

本研究旨在考察一家美国州立医院的出院结果与住院时间和诊断之间的关系。

方法

这项病例系列研究检查了 1945 年至 1954 年期间一家州立医院 5618 名参与者的医疗记录,这是在使用精神药物之前的十年。

结果

在离开医院的 3332 人中,超过一半(59.87%)首次住院的患者在一年内出院,16.95%的患者住院时间超过 5 年。46.17%的入院患者出院后无需再次入院。最常见的诊断包括精神分裂症、其他形式的精神病和酗酒。在引入精神药物的十年前,参与者通常因单次发作而入院,并在几年内返回家中。

结论

尽管研究仅限于一个地点,但研究结果表明,在精神药物作为精神疾病的主要治疗方法之前,出院结果可能比以前认为的更为积极。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ecf9/10018898/bb3add6537f7/12913_2023_9235_Fig1_HTML.jpg

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