Pagan-Rosado Robert, Smith Brandon J, Smither Fantley C, Pingree Matthew J, D'Souza Ryan S
Department of Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, MN, USA.
Department of Anesthesiology and Perioperative Medicine, Division of Pain Medicine, Mayo Clinic Hospital, Rochester, MN, USA.
Case Rep Anesthesiol. 2023 Mar 6;2023:1558183. doi: 10.1155/2023/1558183. eCollection 2023.
This case series aims to highlight the efficacy of peripheral nerve stimulation (PNS) in the treatment of phantom limb pain, as well as provide an alternative method for the treatment of this pain syndrome. In this report, we describe three amputee patients with severe phantom limb pain who obtained substantial analgesia and improvement in physical functionality after implantation of a temporary PNS device. Future studies should assess predictors of successful response or poor response to PNS therapy, such as mental health, environmental stressors, coping skills, and procedural factors. These factors may facilitate an individualized approach for each patient to ensure appropriate candidacy for PNS and better prognosis. Considering that patients in our cohort did not achieve long-lasting benefit after removal of temporary PNS, future research should assess if patients with phantom limb pain would benefit from permanent PNS, rather than temporary PNS.
本病例系列旨在突出周围神经刺激（PNS）治疗幻肢痛的疗效，并提供治疗这种疼痛综合征的替代方法。在本报告中，我们描述了三名患有严重幻肢痛的截肢患者，他们在植入临时PNS设备后获得了显著的镇痛效果，并改善了身体功能。未来的研究应评估PNS治疗成功或反应不佳的预测因素，如心理健康、环境压力源、应对技巧和手术因素。这些因素可能有助于为每位患者制定个性化方法，以确保PNS的合适候选资格并获得更好的预后。鉴于我们队列中的患者在移除临时PNS后未获得持久益处，未来研究应评估幻肢痛患者是否会从永久性PNS而非临时性PNS中获益。
