Kurita Takumi, Tatsumura Masaki, Eto Fumihiko, Funayama Toru, Yamazaki Masashi
Department of Orthopaedic Surgery and Sports Medicine, Tsukuba University Hospital Mito Clinical Education and Training Center, Mito Kyodo General Hospital, Mito, JPN.
Department of Orthopaedic Surgery, Faculty of Medicine, University of Tsukuba, Tsukuba, JPN.
Cureus. 2023 Feb 10;15(2):e34844. doi: 10.7759/cureus.34844. eCollection 2023 Feb.
We treated a patient with pyogenic spondylitis complicated by septic shock, who was saved by emergency surgery. The patient was a 75-year-old man with back pain, fever, and weakness in the lower limbs four days before. Upon admission to our hospital, he had tachycardia, tachypnea, fever, and fluctuating vital signs. His quick sequential organ failure assessment (SOFA) score was 2. Emergent magnetic resonance imaging showed scattered intramuscular abscesses and an epidural abscess. Gram-positive cocci were detected in a blood sample. He was diagnosed with pyogenic spondylitis complicated by sepsis. Intravenous antimicrobial therapy with cefepime, vancomycin, and clindamycin was added. However, he developed tachycardia and hypotension three hours after arrival at our hospital, so he received a blood transfusion and noradrenaline and underwent emergent surgical open drainage since percutaneous drainage was difficult to perform because of scattered abscesses. Paralysis of the proximal lower extremities was recovered after surgery. Postoperatively, the causative organism was found to be methicillin-susceptible and intravenous antimicrobial therapy for 81 days. Three years after surgery, the patient remains free of recurrence with improvement in the activity of daily living to the extent that he could walk. The outcome of our patient suggests that surgery may be a lifesaving measure in cases whose uncontrollable vital signs by pyogenic spondylitis are complicated by sepsis. Preoperative judgment is extremely important in difficult-to-control cases because surgical invasion can be lethal.
我们治疗了一名患有化脓性脊柱炎并伴有感染性休克的患者,该患者通过急诊手术得以挽救。患者为一名75岁男性,四天前出现背痛、发热及下肢无力症状。入院时,他有心动过速、呼吸急促、发热及生命体征波动。其快速序贯器官衰竭评估(SOFA)评分为2分。急诊磁共振成像显示散在的肌肉内脓肿和硬膜外脓肿。血液样本中检测到革兰氏阳性球菌。他被诊断为化脓性脊柱炎合并脓毒症。加用了头孢吡肟、万古霉素和克林霉素进行静脉抗菌治疗。然而,他在入院三小时后出现心动过速和低血压,因此接受了输血和去甲肾上腺素治疗,并因脓肿散在难以进行经皮引流而接受了急诊手术切开引流。术后下肢近端麻痹恢复。术后,发现致病微生物对甲氧西林敏感,并进行了81天的静脉抗菌治疗。手术后三年,患者无复发,日常生活活动能力有所改善,能够行走。我们这位患者的治疗结果表明,对于化脓性脊柱炎导致生命体征无法控制并合并脓毒症的病例,手术可能是一种挽救生命的措施。在难以控制的病例中,术前判断极为重要,因为手术侵袭可能是致命的。