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微创后路固定治疗胸腰椎化脓性脊柱炎,无需前路病灶清创或植骨:一项多中心病例研究

Treatment of Thoracolumbar Pyogenic Spondylitis with Minimally Invasive Posterior Fixation without Anterior Lesion Debridement or Bone Grafting: A Multicenter Case Study.

作者信息

Gamada Hisanori, Funayama Toru, Yamaji Akihiro, Okuwaki Shun, Asada Tomoyuki, Izawa Shigeo, Kumagai Hiroshi, Fujii Kengo, Amano Kuniaki, Shiina Itsuo, Tatsumura Masaki, Uesugi Masafumi, Nakagawa Tsukasa, Yamazaki Masashi, Koda Masao

机构信息

Department of Orthopaedic Surgery, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Japan.

Department of Orthopaedic Surgery, Ibaraki Western Medical Center, 555 Otsuka, Chikusei 308-0813, Japan.

出版信息

J Clin Med. 2023 Jan 25;12(3):932. doi: 10.3390/jcm12030932.

Abstract

The usefulness of minimally invasive posterior fixation without debridement and autogenous bone grafting remains unknown. This multicenter case series aimed to determine the clinical outcomes and limitations of this method for thoracolumbar pyogenic spondylitis. Patients with thoracolumbar pyogenic spondylitis treated with minimally invasive posterior fixation alone were retrospectively evaluated at nine affiliated hospitals since April 2016. The study included 31 patients (23 men and 8 women; mean age, 73.3 years). The clinical course of the patients and requirement of additional anterior surgery constituted the study outcomes. The postoperative numerical rating scale score for lower back pain was significantly smaller than the preoperative score (5.8 vs. 3.6, = 0.0055). The preoperative local kyphosis angle was 6.7°, which was corrected to 0.1° after surgery and 3.7° at the final follow-up visit. Owing to failed infection control, three patients (9.6%) required additional anterior debridement and autogenous bone grafting. Thus, in this multicenter case series, a large proportion of patients with thoracolumbar pyogenic spondylitis could be treated with minimally invasive posterior fixation alone, thereby indicating it as a treatment option for pyogenic spondylitis.

摘要

不进行清创和自体骨移植的微创后路固定的有效性尚不清楚。本多中心病例系列旨在确定这种方法治疗胸腰椎化脓性脊柱炎的临床疗效和局限性。自2016年4月起,对9家附属医院中仅接受微创后路固定治疗的胸腰椎化脓性脊柱炎患者进行回顾性评估。该研究纳入了31例患者(23例男性和8例女性;平均年龄73.3岁)。患者的临床病程以及是否需要额外的前路手术构成了研究结果。术后下背痛的数字评定量表评分显著低于术前评分(5.8对3.6, = 0.0055)。术前局部后凸角为6.7°,术后矫正至0.1°,末次随访时为3.7°。由于感染控制失败,3例患者(9.6%)需要额外进行前路清创和自体骨移植。因此,在本多中心病例系列中,大部分胸腰椎化脓性脊柱炎患者仅采用微创后路固定即可治疗,从而表明它可作为化脓性脊柱炎的一种治疗选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4977/9918103/6773ea5d532e/jcm-12-00932-g001.jpg

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