Editorial: RNAs at the crossroads between effectors and targets; discovery and development of new drugs.
作者信息
Chiappori Federica, Mollica Luca
机构信息
National Research Council-Institute for Biomedical Technologies, Milan, Italy.
L.I.T.A, Department of Medical Biotechnologies and Translational Medicine, University of Milan, Milan, Italy.
出版信息
Front Mol Biosci. 2023 Feb 27;10:1157440. doi: 10.3389/fmolb.2023.1157440. eCollection 2023.
Abstract
摘要
相似文献
1
Editorial: RNAs at the crossroads between effectors and targets; discovery and development of new drugs.社论：处于效应物与靶点之间交叉点的RNA；新药的发现与开发
Front Mol Biosci. 2023 Feb 27;10:1157440. doi: 10.3389/fmolb.2023.1157440. eCollection 2023.
2
Discovery of small molecules that target a tertiary-structured RNA.靶向三级结构 RNA 的小分子的发现。
Proc Natl Acad Sci U S A. 2022 Nov 29;119(48):e2213117119. doi: 10.1073/pnas.2213117119. Epub 2022 Nov 21.
3
Speeding drug discovery targeting RNAs: An iterative "RNA selection-compounds screening cycle" for exploring RNA-small molecule pairs.加速针对 RNA 的药物发现：探索 RNA-小分子对的迭代“RNA 选择-化合物筛选循环”。
Bioorg Med Chem. 2021 Apr 15;36:116070. doi: 10.1016/j.bmc.2021.116070. Epub 2021 Feb 18.
4
Deliver the promise: RNAs as a new class of molecular entities for therapy and vaccination.传递承诺：RNA 作为治疗和疫苗接种的新一类分子实体。
Pharmacol Ther. 2022 Feb;230:107967. doi: 10.1016/j.pharmthera.2021.107967. Epub 2021 Aug 14.
5
Editorial: Current status and perspective on drug targets in tubercle bacilli and drug design of antituberculous agents based on structure-activity relationship.社论：结核杆菌药物靶点的现状与展望以及基于构效关系的抗结核药物设计
Curr Pharm Des. 2014;20(27):4305-6. doi: 10.2174/1381612819666131118203915.
6
Noncoding RNAs Emerging as Drugs or Drug Targets: Their Chemical Modification, Bio-Conjugation and Intracellular Regulation.非编码 RNA 作为药物或药物靶点的出现：它们的化学修饰、生物缀合和细胞内调控。
Molecules. 2022 Oct 9;27(19):6717. doi: 10.3390/molecules27196717.
7
Small RNA discovery in the interaction between barley and the powdery mildew pathogen.大麦与白粉病菌互作中小 RNA 的发现。
BMC Genomics. 2019 Jul 25;20(1):610. doi: 10.1186/s12864-019-5947-z.
8
Reducing Toxicity of Immune Therapy Using Aptamer-Targeted Drug Delivery.利用适体靶向药物递送降低免疫治疗的毒性。
Cancer Immunol Res. 2015 Nov;3(11):1195-200. doi: 10.1158/2326-6066.CIR-15-0194.
9
Artificial miRNAs as therapeutic tools: Challenges and opportunities.人工 miRNA 作为治疗工具：挑战与机遇。
Wiley Interdiscip Rev RNA. 2021 Jul;12(4):e1640. doi: 10.1002/wrna.1640. Epub 2021 Jan 1.
10
'MicroRNA Targets', a new AthaMap web-tool for genome-wide identification of miRNA targets in Arabidopsis thaliana.‘MicroRNA 靶点’，一个新的 AthaMap 网络工具，用于在拟南芥中进行全基因组 miRNA 靶点的鉴定。
BioData Min. 2012 Jul 16;5(1):7. doi: 10.1186/1756-0381-5-7.
本文引用的文献
1
RNA therapy: rich history, various applications and unlimited future prospects.RNA 疗法：丰富的历史、多样的应用和无限的未来前景。
Exp Mol Med. 2022 Apr;54(4):455-465. doi: 10.1038/s12276-022-00757-5. Epub 2022 Apr 19.
2
Spontaneous Embedding of DNA Mismatches Within the RNA:DNA Hybrid of CRISPR-Cas9.DNA错配在CRISPR-Cas9的RNA:DNA杂交体中的自发嵌入
Front Mol Biosci. 2020 Mar 17;7:39. doi: 10.3389/fmolb.2020.00039. eCollection 2020.
3
Structure of an RNA aptamer in complex with the fluorophore tetramethylrhodamine.与荧光染料四甲基罗丹明复合的 RNA 适体的结构。
Nucleic Acids Res. 2020 Jan 24;48(2):949-961. doi: 10.1093/nar/gkz1113.
Zotero 插件