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在一例不明原发恶性肿瘤伴转移性宫颈淋巴结的患者中,F-FDG 全身 PET/CT 上表现为类似原发性恶性肿瘤的同步双侧多灶性沃辛瘤

Synchronous Bilateral Multifocal Warthin's Tumor Mimicking Primary Malignancy on F-FDG Whole Body PET/CT in a Case of Metastatic Cervical Lymph Nodes from Unknown Primary Malignancy.

作者信息

Basheer Shyma, Satish Alamelu, Vallonthaiel Archana George, Sarma Manjit

机构信息

Department of Nuclear Medicine & Molecular Imaging, Amrita Institute of Medical Sciences, Kochi, Kerala, India.

出版信息

World J Nucl Med. 2022 Sep 9;22(1):22-25. doi: 10.1055/s-0042-1750401. eCollection 2023 Mar.

DOI:10.1055/s-0042-1750401
PMID:36923973
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10010857/
Abstract

Warthin's tumor is a benign and frequently encountered salivary gland neoplasm. Bilaterality and multifocality are rare in Warthin's tumor. Synchronous cervical lymph nodal metastasis with unknown primary in a case of Warthin's tumor can raise a suspicion of primary malignancy of the parotid gland. We present a case of bilateral multifocal Warthin's tumor with synchronous squamous cell carcinoma metastasis to the cervical lymph node. F-fluorodeoxyglucose whole body positron emission tomography/computed tomography imaging showed hypermetabolic bilateral multifocal parotid lesions and metastatic cervical lymph node with unknown primary malignancy.

摘要

沃辛瘤是一种常见的良性涎腺肿瘤。双侧性和多灶性在沃辛瘤中较为罕见。沃辛瘤病例中出现同步性颈部淋巴结转移而原发灶不明,可能会使人怀疑腮腺原发性恶性肿瘤。我们报告一例双侧多灶性沃辛瘤并伴有同步性鳞状细胞癌转移至颈部淋巴结的病例。F-氟脱氧葡萄糖全身正电子发射断层扫描/计算机断层扫描成像显示双侧多灶性腮腺病变代谢增高,以及转移性颈部淋巴结,原发恶性肿瘤不明。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef9c/10010857/ae833251e2f4/10-1055-s-0042-1750401-i11721-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef9c/10010857/c079e3374638/10-1055-s-0042-1750401-i11721-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef9c/10010857/ae833251e2f4/10-1055-s-0042-1750401-i11721-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef9c/10010857/c079e3374638/10-1055-s-0042-1750401-i11721-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef9c/10010857/ae833251e2f4/10-1055-s-0042-1750401-i11721-2.jpg

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1
Synchronous Bilateral Multifocal Warthin's Tumor Mimicking Primary Malignancy on F-FDG Whole Body PET/CT in a Case of Metastatic Cervical Lymph Nodes from Unknown Primary Malignancy.在一例不明原发恶性肿瘤伴转移性宫颈淋巴结的患者中,F-FDG 全身 PET/CT 上表现为类似原发性恶性肿瘤的同步双侧多灶性沃辛瘤
World J Nucl Med. 2022 Sep 9;22(1):22-25. doi: 10.1055/s-0042-1750401. eCollection 2023 Mar.
2
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Am J Otolaryngol. 2015 Mar-Apr;36(2):259-63. doi: 10.1016/j.amjoto.2014.11.008. Epub 2014 Nov 27.
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Bilateral multifocal Warthin's tumors in upper neck lymph nodes. Report of a case and brief review of the literature.双侧多发颈部上淋巴结沃辛氏瘤。病例报告及文献复习。
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本文引用的文献

1
Cancer of Unknown Primary: A Review on Clinical Guidelines in the Development and Targeted Management of Patients with the Unknown Primary Site.原发灶不明癌:关于原发部位不明患者诊疗及靶向治疗临床指南的综述
Cureus. 2019 Sep 2;11(9):e5552. doi: 10.7759/cureus.5552.
2
Positron emission tomography in Warthin's tumor mimicking malignancy impacts the evaluation of head and neck patients.模仿恶性肿瘤的沃辛瘤的正电子发射断层扫描影响头颈部患者的评估。
Am J Otolaryngol. 2015 Mar-Apr;36(2):259-63. doi: 10.1016/j.amjoto.2014.11.008. Epub 2014 Nov 27.
3
Warthin's tumour of the parotid gland: our experience.
腮腺沃辛瘤:我们的经验
Acta Otorhinolaryngol Ital. 2013 Dec;33(6):393-7.
4
Bilateral synchronous and multifocal Warthin's tumor mimicking metastases from lung cancer: A rare cause of false positive flourodeoxy glucose positron emission tomography/computed tomography.双侧同步多灶性沃辛瘤酷似肺癌转移:氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描假阳性的罕见原因
Indian J Nucl Med. 2012 Apr;27(2):139-40. doi: 10.4103/0972-3919.110717.
5
Primary squamous cell carcinoma of the parotid gland: a rare entity.腮腺原发性鳞状细胞癌:一种罕见的疾病。
BMJ Case Rep. 2013 May 15;2013:bcr2013009467. doi: 10.1136/bcr-2013-009467.
6
Impact of FDG-PET/CT for the Detection of Unknown Primary Tumours in Patients with Cervical Lymph Node Metastases.氟代脱氧葡萄糖正电子发射断层扫描/计算机断层扫描(FDG-PET/CT)对检测颈部淋巴结转移患者未知原发肿瘤的影响
Mol Imaging Radionucl Ther. 2012 Aug;21(2):63-8. doi: 10.4274/Mirt.344. Epub 2012 Aug 1.
7
Bilateral and multifocal Warthin's tumors of parotid glands: PET/CT imaging.双侧和多灶性腮腺沃辛氏瘤:PET/CT 成像。
Clin Nucl Med. 2012 Feb;37(2):175-7. doi: 10.1097/RLU.0b013e318238f244.