Department of Chemistry, Osmania University, Hyderabad-500 007, India.
Department of Chemistry, School of Physical Sciences, Central University of Kerala, Kasaragod, Kerala 671320, India.
Org Biomol Chem. 2023 Mar 29;21(13):2816-2821. doi: 10.1039/d3ob00121k.
We report here an efficient synthesis of fused bis-indazoles/indazoles a one-pot sequential strategy starting from -azido aldehydes and amines. This novel method involves the sequential formation of 2-indazole followed by a Pd-catalyzed intramolecular cross-dehydrogenative coupling reaction. Overall, this one-pot sequential reaction involved the formation of new five bonds, resulting in the formation of three heterocyclic rings.
我们在此报道了一种从 -叠氮醛和胺出发的一锅法顺序策略高效合成稠合双吲哚/吲哚的方法。这种新方法涉及 2-吲哚的顺序形成，然后是 Pd 催化的分子内交叉脱氢偶联反应。总的来说，这种一锅法顺序反应涉及新的五个键的形成，导致三个杂环的形成。
