Randall S, Buckley C H, Fox H
Department of Pathology, St. Mary's Hospital, Manchester, England.
Int J Gynecol Pathol. 1987;6(2):132-9. doi: 10.1097/00004347-198706000-00005.
The processes of implantation and placentation have been studied in 105 tubal pregnancies. Successful placentation occurred only with plicomural or mural implantations and in these the early development of the placenta occurred in the tube in exactly the same way as it does in the uterus, although tubal placentation was usually membranaceous in nature, possibly because of an inadequate blood supply. Invasion of the placental bed by interstitial extravillous cytotrophoblast occurred in the tube in the same manner as it does in the uterus whereas extravillous trophoblast invaded tubal vessels in the same fashion as it does the spiral arteries in the uterus. Subsequent development of the placenta in the tube differed from that in the uterus in so far as villous invasion of the tubal tissues, with consequent development of the placenta in the subserosa or on the serosa, was common. The ability of the blastocyst to implant in the tube with subsequent normal placentation indicates that these processes are purely a function of trophoblastic tissue, with maternal tissues playing only a passive role.
对105例输卵管妊娠的着床和胎盘形成过程进行了研究。仅在浆膜下或肌壁间着床时才会成功形成胎盘，在这些情况下，胎盘的早期发育在输卵管内的发生方式与在子宫内完全相同，尽管输卵管胎盘通常本质上是膜状的，可能是由于血液供应不足。间质外滋养层细胞侵入胎盘床在输卵管内的发生方式与在子宫内相同，而外滋养层细胞侵入输卵管血管的方式与侵入子宫螺旋动脉的方式相同。输卵管内胎盘的后续发育与子宫内不同，因为绒毛侵入输卵管组织并随后在浆膜下或浆膜上形成胎盘的情况很常见。胚泡在输卵管内着床并随后正常形成胎盘的能力表明，这些过程纯粹是滋养层组织的功能，母体组织仅起被动作用。
