School of Public Health, Fudan University, Shanghai, 200032, China.
Collaborative Innovation Cooperative Unit of National Clinical Research Center for Geriatric Diseases, Shanghai, 200032, China.
BMC Med. 2023 Mar 16;21(1):101. doi: 10.1186/s12916-023-02825-7.
Little is known about life expectancy (LE) with or without frailty. We aimed to estimate the total LE and duration of the state of frailty in China.
This study included older adults aged 65 years and older from the Chinese Longitudinal Healthy Longevity Study (CLHLS). Frailty status was classified into robust, pre-frailty and frailty based on a cumulative deficit model. Total and specific frailty state LEs at 65 years of age were estimated and stratified by demographic characteristics, behaviours, and psychosocial factors using continuous-time multistate modelling.
The total LE of older adults aged 65 years in China was 14.74 years on average (95% CI: 14.52-14.94), of which 4.18 years (95% CI: 4.05-4.30) were robust, 7.46 years (95% CI: 7.31-7.61) pre-frail and 3.10 years (95% CI: 3.01-3.20) frail. Older adults with higher robust LE included men (4.71 years, 95% CI: 4.56-4.88), married older adults (4.41 years, 95% CI: 4.27-4.56), those engaging in physical activity (4.41 years, 95% CI: 4.23-4.59), those consuming fruits daily (4.48 years, 95% CI: 4.22-4.77) and those with high social participation (4.39 years, 95% CI: 4.26-4.53). Increased educational attainment were gradually associated with increased robust LE.
Frailty may lead to a reduced total LE and robust LE of older adults in China. In addition to finding inequalities in total and robust LEs by socioeconomic status, our findings also highlight that healthy behaviours and social participation may ease frailty-related reductions in total and robust LE. Our findings imply that national life-course strategies aimed at frailty screening and psychosocial and behavioural interventions could be important for health aging in China.
关于有或没有衰弱的预期寿命(LE)知之甚少。我们旨在估计中国的总 LE 和衰弱状态的持续时间。
本研究纳入了来自中国长寿纵向研究(CLHLS)的 65 岁及以上的老年人。根据累积缺陷模型,将衰弱状态分为强壮、虚弱前期和虚弱。使用连续时间多状态模型,根据人口统计学特征、行为和心理社会因素,估计和分层 65 岁时的总衰弱状态 LE 和特定衰弱状态 LE。
中国 65 岁老年人的总 LE 平均为 14.74 年(95%CI:14.52-14.94),其中 4.18 年(95%CI:4.05-4.30)为强壮,7.46 年(95%CI:7.31-7.61)为虚弱前期,3.10 年(95%CI:3.01-3.20)为虚弱。具有较高强壮 LE 的老年人包括男性(4.71 年,95%CI:4.56-4.88)、已婚老年人(4.41 年,95%CI:4.27-4.56)、进行体育活动的老年人(4.41 年,95%CI:4.23-4.59)、每天食用水果的老年人(4.48 年,95%CI:4.22-4.77)和社会参与度高的老年人(4.39 年,95%CI:4.26-4.53)。受教育程度的提高与强壮 LE 的增加逐渐相关。
衰弱可能导致中国老年人的总 LE 和强壮 LE 降低。除了发现社会经济地位导致总 LE 和强壮 LE 不平等外,我们的研究结果还表明,健康行为和社会参与可能缓解衰弱导致的总 LE 和强壮 LE 下降。我们的研究结果表明,针对衰弱筛查和心理社会及行为干预的国家生命历程策略对中国的健康老龄化可能很重要。