Department of Cardiology, Franciscus Gasthuis & Vlietland, Rotterdam, the Netherlands.
Department of Cardiology, Thoraxcenter, Erasmus University Medical Center Rotterdam, Erasmus MC, Rotterdam, the Netherlands.
Int J Cardiovasc Imaging. 2023 May;39(5):945-954. doi: 10.1007/s10554-023-02805-1. Epub 2023 Mar 16.
We hypothesize that a novel tailor-made cardiac rehabilitation (CR) program for obesity patients (OPTICARE XL) has better outcomes as compared to usual CR regarding parameters of cardiac function as measured by conventional and advanced transthoracic echocardiography. This is an open-label, randomized controlled trial. Inclusion criteria were: patients referred to CR with a body mass index (BMI) ≥30 kg/m2, and age ≥18 years with either coronary artery disease or nonvalvular atrial fibrillation. The experimental group participated in OPTICARE XL and the controls received the usual CR. Subjects randomized to OPTICARE XL received on top of usual CR behavioural therapy for a healthy diet and an active lifestyle for the first 12 weeks. Also, the exercise program was more tailored. Furthermore, a behavioural after-care program was organized with 6 meetings between weeks 13-52. Transthoracic (speckle tracking) echocardiography was performed at baseline and one-year follow-up. A total of 42 patients completed the follow-up, 21 in both groups. There was a mild but statistically significant reduction in weight over time, however, this was comparable between groups. There was no improvement observed in any of the echocardiographic parameters. In conclusion, cardiac function in obesity patients was not improved one-year after a novel tailor-made CR program (OPTICARE XL) as compared to usual CR.
我们假设，与常规心脏康复（CR）相比，针对肥胖患者的新型定制心脏康复（OPTICARE XL）计划在心脏功能参数方面具有更好的效果，这些参数通过传统和先进的经胸超声心动图进行测量。这是一项开放标签、随机对照试验。纳入标准为：BMI≥30 kg/m2的肥胖患者，年龄≥18 岁，患有冠状动脉疾病或非瓣膜性心房颤动，并被转介至 CR。实验组参加 OPTICARE XL，对照组接受常规 CR。参加 OPTICARE XL 的随机分组患者在最初的 12 周内除了接受常规 CR 的行为疗法外，还接受了健康饮食和积极生活方式的行为治疗。此外，运动方案也更具针对性。此外，在第 13-52 周之间组织了 6 次行为随访计划。在基线和一年随访时进行经胸（斑点追踪）超声心动图检查。共有 42 名患者完成了随访，两组各有 21 名。随着时间的推移，体重有轻微但统计学上显著的下降，但两组之间无差异。任何超声心动图参数均未观察到改善。总之，与常规 CR 相比，肥胖患者在接受新型定制 CR 计划（OPTICARE XL）一年后心脏功能没有改善。
