Pharmacology Department, College of Medicine, Minia University, Minya, 61111, Egypt.
Inflammopharmacology. 2023 Jun;31(3):1559-1560. doi: 10.1007/s10787-023-01180-6. Epub 2023 Mar 16.
The Egyptian immune-modulatory Kelleni's protocol, including nitazoxanide as an integral component, is being safely and effectively practiced to manage SARS-CoV-2, RSV, influenza infections in pediatric, adult and pregnant patients with negligible requirements for the relatively expensive diagnostic molecular tests. Most recently, Kelleni's protocol is being likewise used to manage potential norovirus infection which is currently confused with SARS-CoV-2 Omicron new enterotropic subvariants and the antihistaminic loratadine has been co-administered in selected patients. Notably, Africa has the least mandates, restrictions and SARS-CoV-2 vaccination rates and yet the least COVID-19 mortality.
埃及的免疫调节 Kelleni 方案，包括硝唑尼特作为一个组成部分，正在安全有效地用于管理 SARS-CoV-2、RSV、流感感染，儿科、成人和孕妇患者的相对昂贵的诊断分子检测需求可忽略不计。最近，Kelleni 方案也被用于管理潜在的诺如病毒感染，目前这种感染与 SARS-CoV-2 奥密克戎新肠嗜性亚变种相混淆，并且在选定的患者中联合使用了抗组胺药氯雷他定。值得注意的是，非洲的强制要求、限制和 SARS-CoV-2 疫苗接种率最低，但 COVID-19 死亡率最低。
