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结直肠癌合并睾丸转移:病例报告及文献复习。

Colorectal cancer with testicular metastasis: A case report and literature review.

机构信息

Zhongshan Hospital of Traditional Chinese Medicine Affiliated to Guangzhou University of Chinese Medicine, Zhongshan, China.

Clinical Research and Big Data Laboratory, South China Research Center for Acupuncture and Moxibustion, Medical College of Acu-Moxi and Rehabilitation, Guangzhou University of Chinese Medicine, Guangzhou, China.

出版信息

Medicine (Baltimore). 2023 Mar 17;102(11):e33214. doi: 10.1097/MD.0000000000033214.

Abstract

RATIONALE

Colorectal cancer is the second leading cause of cancer-related deaths in the world. About 50% of patients will have metastases during the course of the disease. The common sites of metastasis are the liver, lung, peritoneum, lymph, etc. Metastatic carcinoma to the testes is uncommon. We found a case of ascending colon cancer metastasized to the testis in the clinic.

PATIENT CONCERNS

We reported a 50-year-old male patient who was found to have testicular metastases >4 years after intestinal cancer surgery, and multiple metastases in the peritoneum and pelvis were found 1 week later.

DIAGNOSES

After enhanced computed tomography and pathological biopsy, the patient was diagnosed with testicular metastasis of colon cancer.

INTERVENTIONS

Capecitabine combined with bevacizumab is currently undergoing palliative treatment.

OUTCOMES

The patients died of tumor progression on June 28, 2021.

LESSONS

The testicular metastasis of colorectal cancer is a sign of peritoneum and multiple metastases. When the testicular metastasis occurs in colorectal cancer patients, it usually indicates that the patient has a poor prognosis.

摘要

背景

结直肠癌是全球癌症相关死亡的第二大主要原因。约 50%的患者在疾病过程中会发生转移。常见的转移部位是肝脏、肺、腹膜、淋巴结等。转移性睾丸癌并不常见。我们在临床上发现了一例升结肠癌转移至睾丸的病例。

病例报告

我们报告了一例 50 岁男性患者,在肠癌手术后 4 年以上发现睾丸转移,1 周后发现腹膜和骨盆多处转移。

诊断

增强 CT 和病理活检后,患者被诊断为结肠癌睾丸转移。

干预措施

卡培他滨联合贝伐珠单抗正在进行姑息治疗。

结果

患者于 2021 年 6 月 28 日因肿瘤进展死亡。

教训

结直肠癌的睾丸转移是腹膜和多发转移的标志。当结直肠癌患者发生睾丸转移时,通常表明患者预后不良。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/135a/10019171/d9d6c5628500/medi-102-e33214-g001.jpg

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