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细胞状态转变:欲擒故纵。

Cell state transitions: catch them if you can.

机构信息

Stem Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

MRC Laboratory of Molecular Biology, Francis Crick Avenue, Cambridge Biomedical Campus, Cambridge CB2 0QH, UK.

出版信息

Development. 2023 Mar 15;150(6). doi: 10.1242/dev.201139. Epub 2023 Mar 17.

Abstract

The Company of Biologists' 2022 workshop on 'Cell State Transitions: Approaches, Experimental Systems and Models' brought together an international and interdisciplinary team of investigators spanning the fields of cell and developmental biology, stem cell biology, physics, mathematics and engineering to tackle the question of how cells precisely navigate between distinct identities and do so in a dynamic manner. This second edition of the workshop was organized after a successful virtual workshop on the same topic that took place in 2021.

摘要

《生物学家公司 2022 年“细胞状态转变:方法、实验系统和模型”研讨会汇集了来自细胞和发育生物学、干细胞生物学、物理学、数学和工程学领域的国际跨学科研究团队,旨在解决细胞如何精确地在不同状态之间转换,以及如何以动态方式完成这一过程的问题。本次研讨会是在 2021 年成功举办的同主题虚拟研讨会之后组织的。

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本文引用的文献

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Rigidity transitions in development and disease.发育和疾病中的刚性转变。
Trends Cell Biol. 2022 May;32(5):433-444. doi: 10.1016/j.tcb.2021.12.006. Epub 2022 Jan 17.
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Cell state transitions: definitions and challenges.细胞状态转变:定义与挑战。
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Cell-type specialization is encoded by specific chromatin topologies.细胞类型特化由特定的染色质拓扑结构编码。
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