Colrain I M, Trinder J, Fraser G, Wilson G V
Department of Psychology, University of Tasmania, Hobart, Australia.
J Appl Physiol (1985). 1987 Nov;63(5):2067-74. doi: 10.1152/jappl.1987.63.5.2067.
There is now considerable evidence which indicates that respiratory activity is different during sleep compared with wakefulness. However, there has been little work on respiratory changes during the transitional period from wakefulness to sleep. The present study was concerned with the quantitative and temporal properties of ventilation during sleep onset. Sleep onsets were studied in five young male adults in a series of single-subject designs in which sleep onsets were replications. The results indicated that during sleep onset the loss of alpha-activity in the electroencephalogram was associated with a substantial, rapid, and highly predictable reduction in ventilation. The change in ventilation was typically due to a reduction in tidal volume and was, in part, secondary to a reduction in metabolic rate. We speculate that the nonmetabolic component may reflect the loss of waking neural drive to respiration, though the present study did not eliminate a variety of other interpretations.
现在有大量证据表明，与清醒状态相比，睡眠期间的呼吸活动有所不同。然而，关于从清醒到睡眠过渡期间的呼吸变化，相关研究很少。本研究关注睡眠开始时通气的定量和时间特性。在一系列单受试者设计中，对五名年轻男性成年人的睡眠开始情况进行了研究，其中睡眠开始情况是可重复的。结果表明，在睡眠开始时，脑电图中α波活动的消失与通气量的大幅、快速且高度可预测的减少有关。通气量的变化通常是由于潮气量的减少，部分原因是代谢率的降低。我们推测，非代谢成分可能反映了清醒状态下对呼吸的神经驱动的丧失，尽管本研究并未排除其他各种解释。
