Department of Forensic Medicine, Section for Toxicology and Drug Analysis, Aarhus University, Aarhus N, Denmark.
Department of Public Health, Aarhus University, Aarhus C, Denmark.
Drug Test Anal. 2023 Jun;15(6):668-677. doi: 10.1002/dta.3472. Epub 2023 Mar 23.
This study examines doping products seized by the police in three regional police districts in Denmark from December 2019 to December 2020. The products, often referred to as performance and image-enhancing drugs (PIEDs), are described in relation to the country of origin, manufacturing company, and the active pharmaceutical ingredient (API) stated on the packaging versus the one identified by subsequent chemical analysis. The study also includes a description of the degree of professionalism by which the products appear according to EU requirements. A total of 764 products were seized during the study period. The products originate from 37 countries, mainly located in Asia (37%), Europe (23%), and North America (13%). One hundred ninety-three different manufacturing companies could be identified from the product packaging. The most frequent compound class was the androgenic anabolic steroids, found in 60% of the products. In 25%-34% of the products, either no or an incorrect API relative to the one stated on the product was found. However, only 7%-10% contain either no API or a compound from a different compound class than the one stated. Most products had a professional appearance fulfilling most EU requirements for packaging information. The study shows that many different companies supply PIEDs to the Danish market and that counterfeit and substandard products are widespread. Many products do, however, appear professional to the user giving an impression of a high-quality product. Although many products are substandard, they most often contain an API from the same compound class as the one labeled.
本研究检查了 2019 年 12 月至 2020 年 12 月期间,丹麦三个地区警方缴获的兴奋剂产品。这些产品通常被称为性能和形象增强药物(PIEDs),根据原产国、制造公司以及包装上注明的活性药物成分(API)与随后化学分析确定的 API 进行描述。该研究还包括根据欧盟要求,对产品的专业程度进行描述。在研究期间共缴获了 764 种产品。这些产品来自 37 个国家,主要来自亚洲(37%)、欧洲(23%)和北美(13%)。从产品包装上可以识别出 193 家不同的制造公司。最常见的化合物类别是雄激素合成类固醇,在 60%的产品中发现。在 25%-34%的产品中,发现要么没有 API,要么与产品上注明的 API 不相符。然而,只有 7%-10%的产品既没有 API,也没有与产品上注明的化合物类别不同的化合物。大多数产品外观专业,符合欧盟对包装信息的大多数要求。该研究表明,许多不同的公司向丹麦市场供应 PIEDs,并且假冒伪劣产品广泛存在。然而,许多产品对用户来说看起来很专业,给人一种高质量产品的印象。尽管许多产品不符合标准,但它们通常含有与标签上相同化合物类别的 API。