Pediatrics Department, Faculty of Medicine, Menoufia University Hospital, Menoufia, Egypt.
Am J Perinatol. 2024 May;41(S 01):e1647-e1656. doi: 10.1055/a-2057-7385. Epub 2023 Mar 18.
The aim of this study was to assess the Neonatal Resuscitation and Adaptation Score (NRAS) value compared with the conventional and combined Apgar scores in predicting neonatal morbidity and mortality.
A prospective cohort study was conducted on 289 neonates delivered at the Menoufia University Hospital. Trained physicians measured conventional Apgar score, combined Apgar score, and NRAS for the neonates at 1 and 5 minutes after delivery in the delivery room. Admitted neonates were followed during their stay to detect any adverse outcomes.
Morbidities such as the need for neonatal intensive care unit admission, mechanical ventilation, surfactant and inotropes administration, need for extensive phototherapy, intravenous immunoglobulin or exchange transfusion, anemia, metabolic acidosis, abnormal liver and kidney function tests, coagulopathies, hypoglycemia, development of seizures in the first 72 hours of life, and positive changes in cranial ultrasound were significantly higher in neonates who lie within low or moderate NRAS than conventional and combined Apgar scores ( < 0.05). As predictors of mortality, the low and moderate values of the NRAS had higher positive predictive values at 1 (73.91 and 30.61%) and 5 minutes (88.89 and 50.94%) than the conventional Apgar scores at 1 (49.18 and 20.53%), 5 minutes (81.25 and 41.27%) and the combined Apgar scores at 1 (35.63 and 12.45%) and 5 minutes (53.1 and 41.33%).
Our study suggests that the NRAS is better than conventional and combined Apgar scores in predicting neonatal morbidity and mortality. Furthermore, a depressed 5-minute NRAS is more predictive of mortality than 1-minute score.
· NRAS is better than conventional and combined Apgar scores in predicting neonatal morbidity.. · NRAS is more predictive of mortality than conventional and combined Apgar scores.. · A depressed 5-minute NRAS is more predictive of mortality than 1-minute score..
本研究旨在评估新生儿复苏适应评分(NRAS)与传统和联合 Apgar 评分在预测新生儿发病率和死亡率方面的价值。
对在梅努菲亚大学医院分娩的 289 例新生儿进行前瞻性队列研究。在分娩室,经过培训的医生在新生儿出生后 1 分钟和 5 分钟时测量传统 Apgar 评分、联合 Apgar 评分和 NRAS。对住院的新生儿进行随访,以检测任何不良结局。
发病率方面,如需要入住新生儿重症监护病房、机械通气、表面活性剂和正性肌力药物治疗、需要广泛光疗、静脉免疫球蛋白或换血、贫血、代谢性酸中毒、肝肾功能检查异常、凝血功能障碍、低血糖、出生后 72 小时内发生惊厥、头颅超声阳性改变等,在 NRAS 低值或中值的新生儿中明显高于传统 Apgar 评分和联合 Apgar 评分(<0.05)。作为死亡率的预测因素,NRAS 的低值和中值在 1 分钟(73.91%和 30.61%)和 5 分钟(88.89%和 50.94%)时的阳性预测值均高于传统 Apgar 评分在 1 分钟(49.18%和 20.53%)、5 分钟(81.25%和 41.27%)和联合 Apgar 评分在 1 分钟(35.63%和 12.45%)和 5 分钟(53.1%和 41.33%)时的阳性预测值。
本研究表明,NRAS 在预测新生儿发病率和死亡率方面优于传统 Apgar 评分和联合 Apgar 评分。此外,5 分钟时的 NRAS 降低比 1 分钟时的评分更能预测死亡率。
·NRAS 在预测新生儿发病率方面优于传统 Apgar 评分和联合 Apgar 评分。·NRAS 在预测死亡率方面优于传统 Apgar 评分和联合 Apgar 评分。·5 分钟时降低的 NRAS 比 1 分钟时的评分更能预测死亡率。