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苯二氮䓬类药物的使用与监狱女性的心理健康:一项横断面研究。

The use of benzodiazepines and the mental health of women in prison: a cross-sectional study.

机构信息

Programa de Pós-Gradução em Ciências da Saúde, Universidade Federal de Ciências da Saúde de Porto Alegre - UFCSPA, Porto Alegre, Rio Grande do Sul, Brasil.

Grupo Hospitalar Conceição - GHC, Porto Alegre, Rio Grande do Sul, Brasil.

出版信息

Sci Rep. 2023 Mar 18;13(1):4491. doi: 10.1038/s41598-023-30604-0.

Abstract

In this article we assessed the prevalence of benzodiazepine (BZD) use in women before and during imprisonment, as well as its related factors and association with symptoms of anxiety, depression, and posttraumatic stress disorder in a quantitative, cross-sectional, analytical study of regional scope. Two female prisons in the Brazilian Prison System were included. Seventy-four women participated by completing questionnaires about their sociodemographic data, BZD use and use of other substances. These questionnaires included the Generalized Anxiety Disorder-7 (GAD-7), Patient Health Questionnaire-9 (PHQ-9), and Posttraumatic Stress Disorder Checklist-Civilian Version (PCL-C). Of the 46 women who reported no BZDs use before arrest, 29 (63%) began using BZDs during imprisonment (p < 0.001). Positive scores for PTSD, anxiety, and depression, as well as associations between BZD use during imprisonment and anxiety (p = 0.028), depression (p = 0.001) and comorbid anxiety and depression (p = 0.003) were found when a bivariate Poisson regression was performed. When a multivariate Poisson regression was performed for tobacco use, the PHQ-9 and GAD-7 scales, BZD use was associated with depression (p = p = 0.008), with tobacco use (p = 0.012), but not with anxiety (p = 0.325). Imprisonment increases the psychological suffering of women, consequently increasing BZD use. Nonpharmacological measures need to be considered in the health care of incarcerated women.

摘要

本文通过一项定量、横断、分析性的区域性研究,评估了女性在入狱前后使用苯二氮䓬类药物(BZD)的流行情况,以及其相关因素与焦虑、抑郁和创伤后应激障碍症状的关系。研究纳入了巴西监狱系统的两所女子监狱。74 名女性通过完成有关其社会人口统计学数据、BZD 使用情况和其他物质使用情况的问卷参与了研究。这些问卷包括广泛性焦虑症 7 项量表(GAD-7)、患者健康问卷 9 项量表(PHQ-9)和创伤后应激障碍清单-平民版(PCL-C)。在报告被捕前未使用 BZD 的 46 名女性中,有 29 名(63%)在监禁期间开始使用 BZD(p<0.001)。当进行双变量泊松回归分析时,发现 PTSD、焦虑和抑郁的阳性评分,以及监禁期间使用 BZD 与焦虑(p=0.028)、抑郁(p=0.001)和共病焦虑和抑郁(p=0.003)之间存在关联。当对烟草使用、PHQ-9 和 GAD-7 量表进行多变量泊松回归分析时,BZD 使用与抑郁(p=0.008)、与烟草使用(p=0.012)相关,但与焦虑无关(p=0.325)。监禁增加了女性的心理痛苦,从而增加了 BZD 的使用。需要在监禁女性的医疗保健中考虑非药物措施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/da8c/10024677/1229866a3a7e/41598_2023_30604_Fig1_HTML.jpg

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