Department of Medicine, University of California San Diego, San Diego, CA, USA.
BMC Womens Health. 2023 Mar 18;23(1):112. doi: 10.1186/s12905-023-02236-z.
Bacterial vaginosis (BV) is one of the most common vaginal dysbiosis in women aged 15-44 years old.
We administered a cross-sectional, single timepoint survey to women ages 18 years or older and who have had bacterial vaginosis (BV). Women completed an anonymous online survey evaluating the impact of BV on their quality of life, how effective different types of treatments were and the amount of self-diagnosed vs. provider diagnosed BV episodes they had.
62 participants completed the anonymous online survey. With a self-reported median number of BV episodes in the past year was 4 (IQR 1-7). Among these women 69.8% reported BV had a negative impact on their sexual health, 67.7% on their physical health, 74.6% on their mental health. More than half of the respondents had used probiotics with oral Lactobacillus sp. (53.2%), mainly by oral route, and over a third had used vaginal boric acid (37.1%). Most women were unaware of Lactobacillus crispatus. Lactobacillus probiotics were more likely to be tried by women who were negatively impacted by BV for overall quality of life (p = 0.033), sexual health (p = 0.002), and mental health (p = 0.006) while boric acid use was more likely to be used by women who were negatively impacted by BV for their sexual health (p = 0.008).
BV is associated with negative quality of life and the women most impacted are seeking alternative treatments such as probiotics (Lactobacillus) and boric acid. There needs to be improvements in BV treatment that include alternative therapy options that have demonstrated efficacy with standardized composition, formulation and dosage.
细菌性阴道病(BV)是 15-44 岁女性中最常见的阴道微生态失调之一。
我们对 18 岁及以上患有细菌性阴道病(BV)的女性进行了横断面、单次时间点调查。女性完成了一份匿名在线调查,评估了 BV 对其生活质量的影响、不同类型治疗的有效性以及她们自我诊断和医生诊断的 BV 发作次数。
62 名参与者完成了匿名在线调查。自我报告的过去一年中 BV 发作中位数为 4 次(IQR 1-7)。在这些女性中,69.8%报告 BV 对她们的性健康有负面影响,67.7%对她们的身体健康有负面影响,74.6%对她们的心理健康有负面影响。超过一半的受访者使用过含有口服乳杆菌属(53.2%)的益生菌,主要通过口服途径,超过三分之一的人使用过阴道硼酸(37.1%)。大多数女性不知道脆拟杆菌。乳杆菌属益生菌更有可能被那些因 BV 对整体生活质量(p=0.033)、性健康(p=0.002)和心理健康(p=0.006)产生负面影响的女性尝试,而硼酸的使用更有可能被那些因 BV 对性健康产生负面影响的女性尝试(p=0.008)。
BV 与生活质量下降有关,受影响最大的女性正在寻求替代治疗方法,如益生菌(乳杆菌)和硼酸。BV 的治疗需要改进,包括替代治疗方法,这些方法已证明具有疗效,且具有标准化的成分、配方和剂量。