Schmidt Lauren K, Keller Krista A, Tonozzi Caroline, Brandão João, Christman Jane, W Stern Adam, Allen-Durrance Ashley E, Alexander Amy B
Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Oklahoma State University, Stillwater, OK 74078, USA.
Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois, Urbana, IL 61821, USA,
J Avian Med Surg. 2023 Mar;36(4):394-399. doi: 10.1647/21-00057.
Intravenous lipid emulsion (ILE) therapy has shown promise as a treatment option for a variety of lipophilic toxins. Two birds presented for suspected ingestion of a toxic substance. A blue-and-gold macaw () presented after chewing a block of bromethalin rodenticide without overt clinical signs at the time of presentation. Additionally, a free-ranging bald eagle () was found weak and depressed near a municipal landfill after presumptive ingestion of pentobarbital. Both birds were treated with ILE therapy for potential intoxication without any adverse events. The macaw was clinically normal after 3 days of hospitalization and at a 1-week reevaluation. The eagle was transferred to a rehabilitation center after markedly improved mentation and strength and was released 7 days later. Clinicians should consider ILE therapy for the treatment of lipophilic toxicities; however, monitoring is recommended for persistent lipemia and other adverse effects that have been reported in the veterinary literature.
静脉注射脂质乳剂（ILE）疗法已显示出有望成为治疗多种亲脂性毒素的一种选择。有两只鸟因疑似摄入有毒物质前来就诊。一只蓝黄金刚鹦鹉（ ）在啃咬了一块溴鼠灵灭鼠剂后前来就诊，就诊时无明显临床症状。此外，一只自由放养的白头鹰（ ）在疑似摄入戊巴比妥后，在城市垃圾填埋场附近被发现虚弱且精神萎靡。两只鸟均接受了ILE疗法以治疗潜在的中毒，未出现任何不良事件。住院3天后以及1周后的复查时，金刚鹦鹉临床状况正常。白头鹰在精神状态和体力明显改善后被转移至康复中心，并于7天后放归自然。临床医生应考虑使用ILE疗法治疗亲脂性中毒；然而，鉴于兽医文献中已报道的持续性脂血症和其他不良反应，建议进行监测。
