State Key Laboratory of Resource Insects, Southwest University, Chongqing, China.
The First Affiliated Hospital of Chongqing Medical and pharmaceutical College, Chongqing, China.
Pest Manag Sci. 2023 Jul;79(7):2287-2298. doi: 10.1002/ps.7454. Epub 2023 Apr 24.
The silkworm, which is considered a model invertebrate organism, was the first insect used for silk production in human history and has been utilized extensively throughout its domestication. However, sericulture has been plagued by various pathogens that have caused significant economic losses. To enhance the resistance of a host to its pathogens,numerous strategies have been developed. For instance, gene-editing techniques have been applied to a wide range of organisms, effectively solving a variety of experimental problems. This review focuses on several common silkworm pests and their pathogenic mechanisms, with a particular emphasis on breeding for disease resistance to control multiple types of silkworm diseases. The review also compares the advantages and disadvantages of transgenic technology and gene-editing systems. Finally, the paper provides a brief summary of current strategies used in breeding silkworm disease resistance, along with a discussion of the establishment of existing technologies and their future application prospects. © 2023 Society of Chemical Industry.
家蚕被认为是一种模式无脊椎动物，是人类历史上第一种用于丝绸生产的昆虫，在其驯化过程中被广泛利用。然而，养蚕业一直受到各种病原体的困扰，这些病原体造成了巨大的经济损失。为了提高宿主对病原体的抵抗力，人们开发了许多策略。例如，基因编辑技术已被应用于广泛的生物中，有效地解决了多种实验问题。本综述重点介绍了几种常见的家蚕害虫及其致病机制，特别强调了通过培育抗病性来控制多种家蚕疾病。该综述还比较了转基因技术和基因编辑系统的优缺点。最后，本文简要总结了目前在家蚕抗病性培育中使用的策略，并讨论了现有技术的建立及其未来的应用前景。© 2023 化学工业协会。
