Bahrampour Juybari Kobra, Rizwan Komal, Faramarz Sanaz, Sadeghi Asie, Amirkhosravi Arian, Hadi Nematollahi Mohammad, Mehrabani Mehrnaz
Abnormal Uterine Bleeding Research Center, Semnan University of Medical Sciences, 35147-99442, Semnan, Iran.
Department of Pharmacology, School of Medicine, Semnan University of Medical Sciences, 35147-99442, Semnan, Iran.
Chem Biodivers. 2023 Apr;20(4):e202200721. doi: 10.1002/cbdv.202200721. Epub 2023 Mar 23.
Some issues, such as their obscure fate or low survival rate into the body during stem cell therapy, should be addressed to boost efficiency. Nanotechnology offers a suitable solution to combat such limitations. Carbon quantum dots (CQDs) are carbon-based nanomaterials and may be used as multi-purpose compounds in stem cell therapy. CQDs are excellent choices for stem cell labeling thanks to their special features such as optical properties and good biocompatibility. Besides, they can modulate the biological function of stem cells, such as their proliferation, homing ability, and differentiation properties. Considering the charismatic feature of CQDs and their broad unique effect on stem cells, the current review aims to summarize the advancements in this field. Hence, we first focused on CQDs synthesis and their applications. In the next section, the stem cell categories will be discussed, and the final part is dedicated to the recent research evaluating the impact of CQDs on stem cell therapy.
一些问题，如它们在干细胞治疗过程中的命运不明或在体内的存活率较低，需要加以解决以提高效率。纳米技术提供了一个合适的解决方案来克服这些限制。碳量子点（CQDs）是碳基纳米材料，可在干细胞治疗中用作多用途化合物。由于其光学性质和良好的生物相容性等特殊特性，碳量子点是干细胞标记的极佳选择。此外，它们可以调节干细胞的生物学功能，如增殖、归巢能力和分化特性。考虑到碳量子点的独特特性及其对干细胞的广泛独特作用，本综述旨在总结该领域的进展。因此，我们首先关注碳量子点的合成及其应用。在下一节中，将讨论干细胞类别，最后一部分专门介绍评估碳量子点对干细胞治疗影响的最新研究。
