Majood Misba, Garg Piyush, Chaurasia Radhika, Agarwal Aakanksha, Mohanty Sujata, Mukherjee Monalisa
Amity Institute of Click Chemistry Research and Studies, Amity University Uttar Pradeshs, Noida 201313, India.
Stem Cells Facility, DBT-Centre of Excellence, All India Institute of Medical Sciences, New Delhi 110029, India.
ACS Omega. 2022 Aug 11;7(33):28685-28693. doi: 10.1021/acsomega.2c03285. eCollection 2022 Aug 23.
Nanotechnology advancements and applications have paved the way for new possibilities in regenerative medicine and tissue engineering. It is a relatively new field that has the potential to improve stem cell differentiation and therapy greatly. Numerous studies have demonstrated that nanomaterials can function as a physiological niche for the formation and differentiation of stem cells. However, quantum dots (QDs), such as carbon quantum dots (CQDs) and graphene quantum dots (GQDs), have shown considerable promise in the field of regenerative medicine. To date, most research has focused on stem cell tracking and imaging using CQDs. However, their interaction with stem cells and the associated possibility for differentiation by selectively focusing chemical signals to a particular lineage has received scant attention. In this mini-review, we attempt to categorize a few pathways linked with the role of CQDs in stem cell differentiation.
纳米技术的进步与应用为再生医学和组织工程带来了新的可能性。这是一个相对较新的领域，具有极大改善干细胞分化和治疗的潜力。众多研究表明，纳米材料可作为干细胞形成和分化的生理微环境。然而，量子点（QDs），如碳量子点（CQDs）和石墨烯量子点（GQDs），在再生医学领域已展现出相当大的前景。迄今为止，大多数研究集中在使用碳量子点进行干细胞追踪和成像。然而，它们与干细胞的相互作用以及通过将化学信号选择性聚焦到特定谱系来实现分化的相关可能性却很少受到关注。在本综述中，我们试图对与碳量子点在干细胞分化中作用相关的一些途径进行分类。
