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与淋巴瘤相关的巨细胞性心肌炎:一项免疫细胞化学研究。

Giant cell myocarditis associated with lymphoma: an immunocytochemical study.

作者信息

Hales S A, Theaker J M, Gatter K C

机构信息

Nuffield Department of Pathology, University of Oxford, John Radcliffe Hospital.

出版信息

J Clin Pathol. 1987 Nov;40(11):1310-3. doi: 10.1136/jcp.40.11.1310.

DOI:10.1136/jcp.40.11.1310
PMID:3693568
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1141230/
Abstract

A case of giant cell myocarditis in a patient with non-Hodgkin's lymphoma is reported. To our knowledge, this is a previously unrecorded association and supports the hypothesis that the aetiology of giant cell myocarditis is related to a changed immune state. Immunohistochemical investigation of this case with a panel of monoclonal antibodies against a range of leucocyte and muscle antigens supports the view that the giant cells have a histiocytic rather than a myogenic origin.

摘要

报告了1例非霍奇金淋巴瘤患者合并巨细胞性心肌炎的病例。据我们所知,这是一种此前未记录的关联,支持了巨细胞性心肌炎的病因与免疫状态改变有关的假说。用一组针对多种白细胞和肌肉抗原的单克隆抗体对该病例进行免疫组织化学研究,支持了巨细胞起源于组织细胞而非肌源性的观点。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/821b/1141230/a57e15946b5e/jclinpath00331-0044-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/821b/1141230/1dceffabd695/jclinpath00331-0045-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/821b/1141230/a57e15946b5e/jclinpath00331-0044-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/821b/1141230/1dceffabd695/jclinpath00331-0045-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/821b/1141230/a57e15946b5e/jclinpath00331-0044-a.jpg

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本文引用的文献

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Granulomatous myocarditis and myositis associated with thymoma.与胸腺瘤相关的肉芽肿性心肌炎和肌炎。
Arch Pathol. 1959 Oct;68:367-73.
2
Giant cell myocarditis.巨细胞性心肌炎
Arch Pathol Lab Med. 1980 May;104(5):245-6.
3
Giant cell myocarditis after mitral valve replacement: case report and studies of the nature of giant cells.二尖瓣置换术后巨细胞性心肌炎:病例报告及巨细胞性质研究
Hum Pathol. 1984 Jun;15(6):585-7. doi: 10.1016/s0046-8177(84)80013-1.
4
Immunohistochemical localization of myoglobin in nonmuscular cells.肌红蛋白在非肌肉细胞中的免疫组织化学定位
Am J Surg Pathol. 1984 Jan;8(1):51-5. doi: 10.1097/00000478-198401000-00005.
5
Immunoenzymatic labeling of monoclonal antibodies using immune complexes of alkaline phosphatase and monoclonal anti-alkaline phosphatase (APAAP complexes).使用碱性磷酸酶与单克隆抗碱性磷酸酶的免疫复合物(碱性磷酸酶抗碱性磷酸酶复合物,APAAP复合物)对单克隆抗体进行免疫酶标记。
J Histochem Cytochem. 1984 Feb;32(2):219-29. doi: 10.1177/32.2.6198355.
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Giant cell myocarditis and myositis. Associated with thymoma and myasthenia gravis.巨细胞性心肌炎和肌炎。与胸腺瘤和重症肌无力相关。
Arch Pathol. 1969 Oct;88(4):359-66.
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Giant cell myocarditis. Light and electron microscopic study.
Arch Pathol. 1970 Aug;90(2):181-8.
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Experimental granulomatous myocarditis: genesis and immunological aspects.实验性肉芽肿性心肌炎:发病机制与免疫学方面
Ann N Y Acad Sci. 1969 Jan 31;156(1):91-104. doi: 10.1111/j.1749-6632.1969.tb16720.x.
9
Giant cell myocarditis: evidence for the macrophage origin of the giant cells.巨细胞性心肌炎:巨细胞源自巨噬细胞的证据
J Clin Pathol. 1985 Feb;38(2):160-4. doi: 10.1136/jcp.38.2.160.
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Acute idiopathic interstitial myocarditis: case report with special reference to morphological characteristics of giant cells.急性特发性间质性心肌炎:病例报告并特别提及巨细胞的形态学特征
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