口面部肉芽肿病的治疗——9个月随访：病例报告

Treatment of Orofacial Granulomatosis-9-Month Follow-up: A Case Report.

作者信息

Sopi Krasniqi Mirlinda, Sllamniku Dalipi Zana, Kastrati Dragidella Donika, Kondirolli Labinota

机构信息

Department of Periodontology and Oral Medicine, University Dentistry Clinical Center of Kosovo, Medical Faculty, University of Prishtina, Prishtina, Kosovo.

Institute of Anatomical Pathology University Clinical Center of Kosovo, Prishtina, Kosovo.

出版信息

Clin Med Insights Case Rep. 2023 Mar 14;16:11795476231160046. doi: 10.1177/11795476231160046. eCollection 2023.

DOI:10.1177/11795476231160046

PMID:36935761

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10017931/

Abstract

Orofacial granulomatosis is a condition that manifests clinically as painless labial enlargement, perioral and mucosal edema, oral ulcers, and gingivitis. It is characterized by non-necrotizing granulomatous inflammation of the oral and maxillofacial region. When the swelling only affects the lips, the pathology is called Miescher's granulomatous cheilitis; however, when it also causes facial paresis and lingua plicata, it is known as Melkersson-Rosenthal syndrome. We report a case that was successfully treated with a combination of a local (intralesional) steroid, a systemic antibiotic, and a systemic steroid. After 6 months of therapy, we observed improvement in gingival hyperplasia and buccal mucosa and lip edema.

摘要

口面部肉芽肿病是一种临床表现为无痛性唇部肿大、口周和黏膜水肿、口腔溃疡及牙龈炎的病症。其特征为口腔颌面部区域的非坏死性肉芽肿性炎症。当肿胀仅累及唇部时，病理学上称为米舍尔肉芽肿性唇炎；然而，当它还导致面部麻痹和皱襞舌时，则被称为梅尔克森 - 罗森塔尔综合征。我们报告了一例通过局部（病灶内）类固醇、全身性抗生素和全身性类固醇联合治疗成功治愈的病例。经过6个月的治疗，我们观察到牙龈增生、颊黏膜及唇部水肿有所改善。