Silva Sousa P, Magalhães C, Cunha A, Castanheira A
Otorhinolaryngology Department, Centro Hospitalar de Trás-os-Montes e Alto Douro, avenida da Noruega, Lordelo, 5000-508 Vila Real, Portugal.
Otorhinolaryngology Department, Centro Hospitalar de Trás-os-Montes e Alto Douro, avenida da Noruega, Lordelo, 5000-508 Vila Real, Portugal.
Eur Ann Otorhinolaryngol Head Neck Dis. 2024 Jan;141(1):33-35. doi: 10.1016/j.anorl.2023.07.003. Epub 2023 Aug 17.
Granulomatous cheilitis is a rare disorder characterized by recurrent, idiopathic, and painless lip swelling. The diagnosis is proven by histopathological examination. The unknown aetiology and poorly understood underlying mechanism contribute to the difficulty in establishing an effective treatment. This case study proposes the effectiveness of radiofrequency therapy in the management of refractory granulomatous cheilitis.
A 68-year-old patient presented with hypertrophy and swelling of the lower lip, and a biopsy revealed actinic cheilitis. The patient underwent lip shaving and an advancement mucosal flap, and definitive histologic examination confirmed the diagnosis of granulomatous cheilitis. No other signs of orofacial granulomatosis were observed, and the complementary aetiological study was negative for systemic disease. The lip swelling reappeared and persisted, which interfered with the quality of life. Hence, radiofrequency therapy was performed in the submucosal and subdermal layers of the lip, resulting in significant aesthetic and functional improvement and no further relapses after five years.
The management of granulomatous cheilitis is challenging. The current mainstay treatment is corticotherapy or reduction cheiloplasty in severe cases. Radiofrequency has potential as a treatment option in debilitating macrocheilia, presenting worthy long-lasting functional and aesthetical results, with minimal morbidity.
肉芽肿性唇炎是一种罕见的疾病，其特征为反复发作、病因不明且无痛性的唇部肿胀。组织病理学检查可确诊。病因不明及潜在机制了解不足导致难以确立有效的治疗方法。本病例研究提出了射频治疗难治性肉芽肿性唇炎的有效性。
一名68岁患者出现下唇肥大和肿胀，活检显示为光化性唇炎。患者接受了唇部切除术和推进黏膜瓣手术，最终组织学检查确诊为肉芽肿性唇炎。未观察到其他口面部肉芽肿病的体征，补充病因学研究未发现全身性疾病。唇部肿胀再次出现并持续存在，影响了生活质量。因此，对唇部黏膜下层和真皮层进行了射频治疗，取得了显著的美学和功能改善，且五年后未再复发。
肉芽肿性唇炎的治疗具有挑战性。目前的主要治疗方法是皮质激素治疗或在严重病例中进行唇部缩小整形术。射频作为治疗衰弱性巨唇的一种选择具有潜力，可产生值得肯定的长期功能和美学效果，且发病率极低。
