Guillery R W, Walsh C
Department of Human Anatomy, Oxford University, United Kingdom.
J Comp Neurol. 1987 Nov 8;265(2):218-23. doi: 10.1002/cne.902650206.
During the study of the developing optic nerve described in the preceding paper (Guillery and Walsh, '87), small bundles of nerve fibers were seen passing between the optic nerve and the ipsilateral hypothalamus of 24-to 27-day-old prenatal ferrets. The bundles appear before any other fiber groups of the retinofugal pathway and are identifiable while the main portions of the retinofugal system are growing into the optic tracts. The bundles, made up of 50 or more axons, leave the optic nerve, emerge through the otherwise continuous layer of subpial glia and through the basal lamina of the nerve, run a short, naked, extracerebral course among collagen fibers and presumed fibroblasts, and then re-enter the central nervous system, passing rostrally and dorsally to the superficial parts of the ipsilateral hypothalamus away from the region of the chiasm. These fibers represent the earliest link between the optic nerve and the brain, but their course is not followed by the majority of retinofugal fibers developing later, which pass toward one or the other optic tract.
在之前的论文（Guillery和Walsh，1987年）中所描述的对视神经发育的研究过程中，在24至27日龄的产前雪貂中，可见小束神经纤维在视神经和同侧下丘脑之间穿过。这些纤维束在视网膜神经纤维通路的任何其他纤维群之前出现，并且在视网膜神经纤维系统的主要部分长入视束时就可以识别。这些由50根或更多轴突组成的纤维束离开视神经，穿过原本连续的软膜下神经胶质层并穿过神经的基膜，在胶原纤维和推测的成纤维细胞之间进行一段短的、无髓鞘的脑外行程，然后重新进入中枢神经系统，向头侧和背侧穿过同侧下丘脑的浅表部分，远离交叉区域。这些纤维代表了视神经与脑之间最早的联系，但大多数后来发育的视网膜神经纤维并不沿着它们的路径走行，而是朝向一侧或另一侧的视束。
