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以氨基为合成核仁定位信号的阳离子寡肽用于核仁染色探针的合理设计

Cationic Oligopeptides with Amino Groups as Synthetic Nucleolar Localization Signals for the Rational Design of Nucleolus-Staining Probes.

作者信息

Suzuki Michiyuki, Sato Yusuke, Togashi Nao, Nishizawa Seiichi

机构信息

Department of Chemistry, Graduate School of Science, Tohoku University, Sendai 980-8578, Japan.

出版信息

ACS Omega. 2023 Feb 28;8(10):9592-9596. doi: 10.1021/acsomega.3c00116. eCollection 2023 Mar 14.

Abstract

Cationic oligopeptides with amino groups were found to function as synthetic nucleolar localization signals for directing various fluorophores to the nucleolus with high selectivity in the cells with a view toward the development of nucleolus-staining probes.

摘要

发现带有氨基的阳离子寡肽可作为合成核仁定位信号,用于在细胞中将各种荧光团以高选择性导向核仁,以期开发核仁染色探针。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fc1d/10018684/a3d393956802/ao3c00116_0002.jpg

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