Harrison Theodore E, Bowler Jannice, Levins Todd N, Reeves K Dean
Regenerative Medicine, Private Practice, Sydney, CAN.
Regenerative Medicine, Private Practice, Victoria, CAN.
Cureus. 2023 Mar 13;15(3):e36099. doi: 10.7759/cureus.36099. eCollection 2023 Mar.
Platelet-rich plasma (PRP), an inexpensive yet powerful treatment modality, is widely used but poorly understood. Three areas of unmet need are the ability to compare results using differing centrifuges and methods; translating a study result into a specific practice; and estimating yield and dosage without the benefit of an in-office hematology analyzer. PRPCalc2 is a set of software tools that facilitates these goals. The app consists of software tools that (1) calculate the appropriate radius for centrifugation, (2) calculate the correct revolutions per minute (RPM) for the centrifuge, (3) calculate the mean yield for the method and its confidence interval, and (4) calculate platelet dosage. Using these tools, a practitioner with any centrifuge can create and validate their own PRP preparation method and then use it to create a standardized PRP.
富含血小板血浆(PRP)是一种价格低廉却效果显著的治疗方式,虽被广泛应用,但人们对其了解甚少。目前有三个尚未满足的需求领域:使用不同离心机和方法时比较结果的能力;将研究结果转化为具体实践;以及在没有办公室血液分析仪的情况下估算产量和剂量。PRPCalc2是一套有助于实现这些目标的软件工具。该应用程序由以下软件工具组成:(1)计算离心的合适半径;(2)计算离心机的正确每分钟转速(RPM);(3)计算该方法的平均产量及其置信区间;(4)计算血小板剂量。使用这些工具,任何离心机的从业者都可以创建并验证自己的PRP制备方法,然后用它来制备标准化的PRP。