一种治疗顽固性眶周皮肤幼年性黄色肉芽肿的多方面方法。
A Multifaceted Approach to Treatment of Recalcitrant Cutaneous Periorbital Juvenile Xanthogranuloma.
作者信息
Van Brummen Alexandra, Jacobs Sarah, Feng Shu, Li Emily, J Amadi Arash
机构信息
Department of Ophthalmology, University of Washington, Seattle, WA, USA.
Department of Ophthalmology, University of Alabama, Birmingham, AL, USA.
出版信息
J Ophthalmic Vis Res. 2023 Feb 21;18(1):130-134. doi: 10.18502/jovr.v18i1.12733. eCollection 2023 Jan-Mar.
PURPOSE
To demonstrate novel treatments for patients with high juvenile xanthogranuloma (JXG) eyelid lesion burden.
CASE REPORT
A 14-year-old girl was referred to the oculoplastic surgery service for management of worsening extensive bilateral eyelid and adnexal lesions in the setting of JXG. The patient underwent intra-lesional steroid injections, serial excisions, and reconstruction with skin grafts. She was subsequently treated with CO laser-assisted topical steroid application, which resulted in lesion regression.
CONCLUSION
A novel multimodal approach to treatment of severe periocular JXG, incorporating surgical debulking, skin autograft, CO2 laser, and intra-lesional steroids, can be effective for lesion control.
目的
展示针对青少年黄色肉芽肿（JXG）眼睑病变负担较重患者的新型治疗方法。
病例报告
一名14岁女孩因JXG导致双侧眼睑及附属器病变广泛且病情加重，被转诊至眼整形手术科室。患者接受了病变内类固醇注射、系列切除术以及皮肤移植重建术。随后她接受了二氧化碳激光辅助局部类固醇应用治疗，病变得以消退。
结论
一种新型的多模式方法用于治疗严重的眼周JXG，包括手术减容、自体皮肤移植、二氧化碳激光和病变内类固醇注射，可有效控制病变。
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