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髓内钉与接骨板内固定治疗伴有节段性骨缺损的胫骨近端关节外骨折的生物力学比较

Biomechanical comparison of intramedullary nail and plate osteosynthesis for extra-articular proximal tibial fractures with segmental bone defect.

作者信息

Gao Weihang, Zhao Ke, Guo Yuanyuan, Xie Mao, Feng Xiaobo, Liu Ping, Xie Xin, Fu Dehao

机构信息

Department of Orthopaedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Department of Orthopaedics, Liyuan Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

出版信息

Front Bioeng Biotechnol. 2023 Mar 3;11:1099241. doi: 10.3389/fbioe.2023.1099241. eCollection 2023.

Abstract

Proximal tibial fractures are common, but the current available internal fixation strategies remain debatable, especially for comminuted fractures. This study aimed to compare the biomechanical stability of three internal fixation strategies for extra-articular comminuted proximal tibial fractures. A total of 90 synthetic tibiae models of simulated proximal tibial fractures with segmental bone defects were randomly divided into three groups: Single lateral plating (LP), double plating (DP) and intramedullary nailing (IN). Based on the different number of fixed screws, the above three groups were further divided into nine subgroups and subjected to axial compression, cyclic loading and static torsional testing. The subgroup of intramedullary nailing with five proximal interlocking screws showed the highest axial stiffness of 384.36 ± 35.00 N/mm. The LP group obtained the lowest axial stiffness performance with a value of 96.59 ± 16.14 N/mm. As expected, the DP group offered significantly greater biomechanical stability than the LP group, with mean static axial stiffness and mean torque increasing by approximately 200% and 50%, respectively. According to static torsional experiments, the maximum torque of the DP subgroup was 3,308.32 ± 286.21 N mm, which outperformed all other groups in terms of torsional characteristics. Utilizing more than four distal screws did not provide improved biomechanical stability in the LP or DP groups, while a substantial increase in the biomechanical stability of DP was obtained when an additional medial plate was used. For the intramedullary nailing group, increasing the number of proximal interlocking screws could significantly improve biomechanical stability, and the intramedullary nailing with three proximal interlocking screws had similar static and cyclic stiffness as the DP group. The intramedullary nailing with five proximal screws had better axial stability, whereas DP had better torsional stability.

摘要

胫骨近端骨折很常见,但目前可用的内固定策略仍存在争议,尤其是对于粉碎性骨折。本研究旨在比较三种内固定策略用于关节外粉碎性胫骨近端骨折的生物力学稳定性。总共90个模拟胫骨近端骨折并伴有节段性骨缺损的合成胫骨模型被随机分为三组:单侧钢板固定(LP)、双侧钢板固定(DP)和髓内钉固定(IN)。基于不同数量的固定螺钉,上述三组进一步分为九个亚组,并进行轴向压缩、循环加载和静态扭转试验。使用五枚近端交锁螺钉的髓内钉亚组显示出最高的轴向刚度,为384.36±35.00N/mm。LP组获得最低的轴向刚度性能,值为96.59±16.14N/mm。正如预期的那样,DP组提供的生物力学稳定性明显高于LP组,平均静态轴向刚度和平均扭矩分别增加了约200%和50%。根据静态扭转实验,DP亚组的最大扭矩为3308.32±286.21N·mm,在扭转特性方面优于所有其他组。在LP组或DP组中,使用超过四枚远端螺钉并不能提高生物力学稳定性,而当使用额外的内侧钢板时,DP组的生物力学稳定性有显著提高。对于髓内钉固定组,增加近端交锁螺钉的数量可显著提高生物力学稳定性,使用三枚近端交锁螺钉的髓内钉固定与DP组具有相似的静态和循环刚度。使用五枚近端螺钉的髓内钉具有更好的轴向稳定性,而DP具有更好的扭转稳定性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df53/10020223/190ef173fe18/fbioe-11-1099241-g001.jpg

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