Lechtholz-Zey Elizabeth, Matti Nawar Y, Fredrickson Vance L, Buchanan Ian, Donoho Daniel A
Orthopaedic Surgery, Keck School of Medicine of University of South California, Los Angeles, USA.
Pathology, Southwest Healthcare System, Los Angeles, USA.
Cureus. 2023 Feb 15;15(2):e35033. doi: 10.7759/cureus.35033. eCollection 2023 Feb.
Aneurysmal bone cysts are benign osseous lesions containing blood-filled cavities separated by walls of connective tissue. They can be difficult to identify clinically due to similarities in presentation, imaging, and histology with other pathologies. Specifically, it is important to distinguish these benign lesions from malignant processes, as both surgical and medical management differ. We present the case of a 21-year-old patient who presented with impaired motor and sensory function in his lower extremities. Radiologic findings were concerning for an invasive neoplasm, and the intraoperative frozen section supported this conclusion. However, an additional histological investigation was confirmatory for a diagnosis of an aneurysmal bone cyst. The patient underwent corpectomy, laminectomy, and a posterior spinal fusion, and regained motor and sensory function shortly thereafter. This report details the importance of considering aneurysmal bone cysts in the differential of infiltrative bone lesions, despite their benign nature, as medical and surgical management can vary greatly.
骨囊肿是一种良性骨病变,含有由结缔组织壁分隔的充满血液的腔隙。由于其在临床表现、影像学和组织学上与其他病理情况相似,临床上可能难以识别。具体而言,将这些良性病变与恶性病变区分开来很重要,因为手术和药物治疗方法有所不同。我们报告了一例21岁患者,其下肢运动和感觉功能受损。放射学检查结果提示为侵袭性肿瘤,术中冰冻切片支持这一结论。然而,进一步的组织学检查确诊为骨囊肿。患者接受了椎体切除、椎板切除和后路脊柱融合术,术后不久运动和感觉功能恢复。本报告详细阐述了尽管骨囊肿本质为良性,但在鉴别浸润性骨病变时考虑骨囊肿的重要性,因为药物和手术治疗可能差异很大。