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哈伯综合征:一例报告。

Haber's Syndrome: A Case Report.

作者信息

Aljoudi Sarah B, Tallab Mawaddah, Al Hawsawi Khalid

机构信息

Dermatology, King Abdulaziz University Faculty of Medicine, Jeddah, SAU.

Dermatology, King Fahad General Hospital, Jeddah, SAU.

出版信息

Cureus. 2023 Feb 13;15(2):e34906. doi: 10.7759/cureus.34906. eCollection 2023 Feb.

Abstract

Haber's syndrome is an autosomal dominant, rare genodermatosis characterized by photosensitive, persistent facial erythema associated with reticulated hyperpigmentation. We present a case of an eight-year-old healthy Saudi girl who presented with facial erythema and generalized reticulated hyperpigmentation. Systematic review and laboratory studies were unremarkable. Histopathological examination revealed hyperpigmentation of the basilar keratinocytes with mild digitated elongations of the rete ridges. The patient was diagnosed with early-onset clinical presentation of Haber's syndrome. In this report, Haber's syndrome is reviewed, and differential diagnoses of reticulated hyperpigmentation are discussed.

摘要

哈伯综合征是一种常染色体显性遗传的罕见遗传性皮肤病,其特征为光敏性、持续性面部红斑并伴有网状色素沉着。我们报告一例8岁健康沙特女孩,她出现面部红斑和全身性网状色素沉着。系统检查和实验室检查均无异常。组织病理学检查显示基底角质形成细胞色素沉着, rete嵴轻度指状伸长。该患者被诊断为哈伯综合征的早发临床表现。本报告对哈伯综合征进行了综述,并讨论了网状色素沉着的鉴别诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7931/10015217/5239e2103831/cureus-0015-00000034906-i01.jpg

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