College of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai, United Arab Emirates.
Hamdan Bin Mohammed College of Dental Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai, United Arab Emirates.
Int J Public Health. 2023 Mar 3;68:1605421. doi: 10.3389/ijph.2023.1605421. eCollection 2023.
The COVID-19 pandemic has greatly impacted health and care workers (HCW) globally, whom are considered at greater risk of infection and death. This study aims to document emerging evidence on disease prevalence, clinical outcomes, and vaccination rates of HCWs. Three databases were surveyed resulting on 108 final articles between July-December 2020 (period 1) and January-June 2021 (period 2). Amongst the overall 980,000 HCWs identified, in period 1, the estimates were 6.1% (95% CI, 4.1-8.8) for the PCR positivity rate. Regarding outcomes, the hospitalization prevalence was 1.6% (95% CI, 0.7-3.9), and mortality rate of 0.3% (95% CI, 0.1-0.8). In period 2, the PCR positivity rate was 8.1% (95% CI, 4.6-13.8). Analysis of outcomes revealed a hospitalization rate of 0.7% (95% CI 0.3-1.8), and average mortality rate of 0.3% (95% CI 0.1-0.9). Our analysis indicated a HCW vaccination rate of 59.0% (95% CI, 39.4-76.1). Studies from the latter half of 2020 to the first half of 2021 showed a slight increasing trend in PCR positivity among HCW, along with improved clinical outcomes in the 1-year period of exposure. These results correlate well with the improving uptake of COVID-19 vaccination globally.
新型冠状病毒肺炎（COVID-19）大流行在全球范围内对卫生保健工作者（HCW）造成了重大影响，他们被认为感染和死亡的风险更高。本研究旨在记录 HCW 疾病流行率、临床结局和疫苗接种率的最新证据。调查了三个数据库，最终纳入了 2020 年 7 月至 12 月（第 1 期）和 2021 年 1 月至 6 月（第 2 期）期间的 108 篇最终文章。在所确定的 98 万名 HCW 中，第 1 期的聚合酶链反应（PCR）阳性率估计为 6.1%（95%可信区间，4.1-8.8）。关于结局，住院率为 1.6%（95%可信区间，0.7-3.9），死亡率为 0.3%（95%可信区间，0.1-0.8）。第 2 期的 PCR 阳性率为 8.1%（95%可信区间，4.6-13.8）。对结局的分析显示，住院率为 0.7%（95%可信区间 0.3-1.8），平均死亡率为 0.3%（95%可信区间 0.1-0.9）。我们的分析表明 HCW 疫苗接种率为 59.0%（95%可信区间，39.4-76.1）。2020 年下半年至 2021 年上半年的研究表明，HCW 的 PCR 阳性率呈轻微上升趋势，在接触后的 1 年期间临床结局有所改善。这些结果与全球 COVID-19 疫苗接种率的提高密切相关。
