Department of Biostatistics and Epidemiology, Hudson College of Public Health, University of Oklahoma Health Sciences Center, Oklahoma City, OK.
Division of Pediatric Hematology/Oncology and Division of Public Health Sciences in Department of Surgery, Washington University School of Medicine Program in Occupational Therapy, St. Louis, MO.
Blood Adv. 2023 Aug 8;7(15):4064-4071. doi: 10.1182/bloodadvances.2023009792.
The American Society of Hematology Clinical Research Training Institute (CRTI) is a clinical research training program with a competitive application process. The objectives were to compare application scores based on applicant and reviewer sex and underrepresented minority (URM) status. We included applications to CRTI from 2003 to 2019. The application scores were transformed into a scale from 0 to 100 (100 was the strongest). The factors considered were applicant and reviewer sex and URM status. We evaluated whether there was an interaction between the characteristics and time related to application scores. In total, 713 applicants and 2106 reviews were included. There was no significant difference in scores according to applicant sex. URM applicants had significantly worse scores than non-URM applicants (mean [standard error] 67.9 [1.56] vs 71.4 [0.63]; P = .0355). There were significant interactions between reviewer sex and time (P = .0030) and reviewer URM status and time (P = .0424); thus, results were stratified by time. For the 2 earlier time periods, male reviewers gave significantly worse scores than did female reviewers; this difference did not persist for the most recent time period. The URM reviewers did not give significantly different scores across time periods. URM applicants received significantly lower scores than non-URM applicants. The impact of reviewer sex and URM status changed over time. Although male reviewers gave lower scores in the early periods, this effect did not persist in the late period. Efforts are required to mitigate the impact of applicant URM status on application scores.
美国血液学会临床研究培训研究所 (CRTI) 是一个具有竞争申请流程的临床研究培训计划。目的是根据申请人和评审员的性别以及代表性不足的少数族裔 (URM) 状况比较申请评分。我们纳入了 2003 年至 2019 年 CRTI 的申请。将申请评分转换为 0 到 100 的量表（100 是最强的）。考虑的因素包括申请人和评审员的性别以及 URM 状况。我们评估了特征与申请评分之间是否存在与时间相关的相互作用。总共有 713 名申请人和 2106 次评审。申请人的性别与评分无显著差异。URM 申请人的评分明显低于非 URM 申请人（平均值 [标准误差] 67.9 [1.56] 与 71.4 [0.63]；P =.0355）。评审员的性别和时间之间存在显著的交互作用（P =.0030）以及评审员 URM 状况和时间之间存在显著的交互作用（P =.0424）；因此，根据时间进行分层分析。对于前两个时期，男性评审员的评分明显低于女性评审员；这一差异在最近的时期并不持续。URM 评审员在不同时期的评分没有显著差异。URM 申请人的评分明显低于非 URM 申请人。评审员性别和 URM 状况的影响随时间而变化。尽管男性评审员在早期阶段的评分较低，但这种影响在后期阶段并未持续。需要努力减轻申请人 URM 状况对申请评分的影响。
