Department of Otorhinolaryngology, Karolinska University Hospital, Stockholm, Sweden.
Karolinska Institutet, Stockholm, Sweden.
Otolaryngol Head Neck Surg. 2023 May;168(5):1025-1033. doi: 10.1002/ohn.188. Epub 2023 Jan 22.
To assess the incidence of Bell's palsy in pregnant and postpartum women. Additionally, to compare facial outcomes in terms of Sunnybrook score following Bell's palsy with regard to corticosteroid treatment and other confounding factors.
Retrospective case-control study.
University Hospital, Stockholm, Sweden.
All women with Bell's palsy in pregnancy or postpartum (6 weeks after birth) with a computerized medical chart in the Stockholm Region 2005 to 2015 were included. The total number of births in the region during this period was retrieved from the Swedish Medical Birth Register. Nonpregnant age-matched women with Bell's palsy served as controls. Characteristics, medication, and Sunnybrook scores were collected. Risk factors for incomplete recovery (Sunnybrook score <96) at 3 months were calculated by logistic regression.
In total, 182 pregnant and postpartum women with Bell's palsy were identified. The estimated incidence among pregnant and postpartum women was 60.5/100,000 person-years. The mean Sunnybrook score at 3 months was 74 among pregnant and postpartum women and 83 for controls (p = .002). At 12 months, Sunnybrook score was 81 and 89, respectively (p = .017). Only one-third of the pregnant women received corticosteroid treatment.
The incidence of Bell's palsy in pregnancy and postpartum was 60.5 per 100,000 women and year in the Stockholm Region. Sunnybrook score was poorer in pregnant women compared with postpartum and nonpregnant women throughout. Corticosteroid treatment had little effect on any patients, however, only one-third of the pregnant women received this treatment.
评估妊娠及产后女性贝尔氏麻痹的发病率。此外,比较贝尔氏麻痹后采用类固醇治疗和其他混杂因素的情况下,根据桑尼布鲁克评分(Sunnybrook score)评估面部结局。
回顾性病例对照研究。
瑞典斯德哥尔摩大学医院。
2005 年至 2015 年期间,在斯德哥尔摩地区,所有妊娠或产后(产后 6 周)患有贝尔氏麻痹且计算机化病历可查的女性均被纳入研究。在此期间,该地区的总分娩人数从瑞典医疗出生登记处获得。同期患有贝尔氏麻痹但未妊娠的年龄匹配女性作为对照。收集特征、用药情况和桑尼布鲁克评分。采用 logistic 回归计算 3 个月时(桑尼布鲁克评分<96)不完全恢复的风险因素。
共确定 182 例妊娠和产后患有贝尔氏麻痹的女性。妊娠和产后女性的估计发病率为 60.5/100,000 人年。妊娠和产后女性 3 个月时的平均桑尼布鲁克评分为 74,对照组为 83(p=0.002)。12 个月时,桑尼布鲁克评分分别为 81 和 89(p=0.017)。只有三分之一的孕妇接受了皮质类固醇治疗。
在斯德哥尔摩地区,妊娠和产后贝尔氏麻痹的发病率为每 100,000 名女性和每年 60.5 例。与产后和未妊娠女性相比,孕妇的桑尼布鲁克评分始终更差。皮质类固醇治疗对任何患者的效果都不大,然而,只有三分之一的孕妇接受了这种治疗。